---
res:
  bibo_abstract:
  - "Within the plant endomembrane system, the vesicle coat protein clathrin localizes
    to the plasma membrane (PM) and the trans-Golgi Network/early endosome (TGN/EE).
    While the role of clathrin in endocytosis at the PM is well established, its function
    at TGN/EE, presumably in late secretion (trafficking from the TGN/EE to the cell
    surface) or en route to the vacuole, is debated. Similarly debated are potential
    homeostatic mechanisms balancing the trafficking routes, especially endocytosis
    and late secretion.\r\nWe address these questions in Arabidopsis thaliana using
    conditional silencing of CLATHRIN HEAVY CHAIN (CHC), conditional overexpression
    of the clathrin uncoating factor AUXILIN-LIKE1, and secretory mutants.\r\nCHC
    silencing interferes with trafficking of cargoes destined for the apoplast and
    the PM, supporting a function of clathrin in late secretion. The secretory cargoes
    become abnormally rerouted from the TGN/EE to the vacuole. Unlike CHC silencing,
    overexpression of AUXILIN-LIKE1 selectively inhibits clathrin-mediated endocytosis
    while secretion continues normally at early points of induction. Conversely, secretory
    mutants exhibit a reduced PM recruitment of clathrin, and variably, of the TPLATE
    endocytic component.\r\nTogether, our data show a role of clathrin in secretion
    and suggest secretion as a fundamental trafficking process to which endocytosis
    is adjusted by a weak homeostatic mechanism.@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Maciek
      foaf_name: Adamowski, Maciek
      foaf_surname: Adamowski
      foaf_workInfoHomepage: http://www.librecat.org/personId=45F536D2-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-6463-5257
  - foaf_Person:
      foaf_givenName: Adam
      foaf_name: Gackowski, Adam
      foaf_surname: Gackowski
  - foaf_Person:
      foaf_givenName: Ivana
      foaf_name: Matijevic, Ivana
      foaf_surname: Matijevic
      foaf_workInfoHomepage: http://www.librecat.org/personId=83c17ce3-15b2-11ec-abd3-f486545870bd
  - foaf_Person:
      foaf_givenName: Saqer S.
      foaf_name: Alotaibi, Saqer S.
      foaf_surname: Alotaibi
  - foaf_Person:
      foaf_givenName: Jiří
      foaf_name: Friml, Jiří
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  bibo_doi: 10.1111/nph.71454
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0028-646X
  - http://id.crossref.org/issn/1469-8137
  dct_language: eng
  dct_publisher: Wiley@
  dct_title: The role of clathrin in post‐Golgi secretion in plant cells@
  fabio_hasPubmedId: '42477503'
...
