---
OA_place: publisher
_id: '22745'
acknowledgement: "This research was supported by the Scientific Service Units of Institute
  of Science and\r\nTechnology Austria through resources provided by the Lab Support
  Facility and Electron\r\nMicroscopy Facility at ISTA. Monoclonal Antibody Facility
  at Max Perutz laboratories are\r\nacknowledged for raising anti-pSer1022 MDA5 antibody.
  Proteomics core facility CEITEC MUNI\r\nBrno, namely David Pospíšil, are acknowledged
  for their help with measuring MS data as well\r\nas help with interpreting them
  and the introduction into MS data analysis. CIISB, Instruct-CZ\r\nCentre of Instruct-ERIC
  EU consortium, funded by MEYS CR infrastructure project LM2023042,\r\nis gratefully
  acknowledged for the financial support of the measurements at the CEITEC\r\nProteomics
  Core Facility. Computational resources were provided by the e-INFRA CZ project\r\n(ID:90254),
  supported by MEYS CR.\r\nThis work was supported by the Austrian Science Fund (FWF)
  grant F8003-B RNA-DECO:\r\nDecorating RNA for a purpose (10.55776/F80)."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: David
  full_name: Michalik, David
  id: B9577E20-AA38-11E9-AC9A-0930E6697425
  last_name: Michalik
citation:
  ama: Michalik D. Mechanistic insights into MDA5 selectivity and regulation. 2026.
    doi:<a href="https://doi.org/10.15479/AT-ISTA-22745">10.15479/AT-ISTA-22745</a>
  apa: Michalik, D. (2026). <i>Mechanistic insights into MDA5 selectivity and regulation</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22745">https://doi.org/10.15479/AT-ISTA-22745</a>
  chicago: Michalik, David. “Mechanistic Insights into MDA5 Selectivity and Regulation.”
    Institute of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22745">https://doi.org/10.15479/AT-ISTA-22745</a>.
  ieee: D. Michalik, “Mechanistic insights into MDA5 selectivity and regulation,”
    Institute of Science and Technology Austria, 2026.
  ista: Michalik D. 2026. Mechanistic insights into MDA5 selectivity and regulation.
    Institute of Science and Technology Austria.
  mla: Michalik, David. <i>Mechanistic Insights into MDA5 Selectivity and Regulation</i>.
    Institute of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22745">10.15479/AT-ISTA-22745</a>.
  short: D. Michalik, Mechanistic Insights into MDA5 Selectivity and Regulation, Institute
    of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-08-21T09:29:34Z
date_published: 2026-08-21T00:00:00Z
date_updated: 2026-08-28T08:34:46Z
day: '21'
ddc:
- '572'
degree_awarded: PhD
department:
- _id: CaBe
- _id: GradSch
doi: 10.15479/AT-ISTA-22745
doi_confirm: '1'
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  date_created: 2026-08-26T08:46:02Z
  date_updated: 2026-08-26T08:46:02Z
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has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-sa/4.0/
month: '08'
oa_version: Published Version
page: '182'
project:
- _id: 059C9F64-7A3F-11EA-A408-12923DDC885E
  grant_number: F8003
  name: 'RNAdeco: decorating RNA for a purpose'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Carrie A
  full_name: Bernecky, Carrie A
  id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
  last_name: Bernecky
  orcid: 0000-0003-0893-7036
title: Mechanistic insights into MDA5 selectivity and regulation
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  name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
    BY-SA 4.0)
  short: CC BY-SA (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...