---
res:
  bibo_abstract:
  - 'Robust oxygenic photosynthesis requires the efficient assembly and repair of
    the multi-subunit oxygen-evolving photosystem II (PSII) complex. Previous cryogenic
    electron microscopy (cryo-EM) structures of PSII assembly/disassembly intermediates
    have relied on the analysis of deletion mutants or removal of PSII subunits in
    vitro. Here we report the cryo-EM structures of naturally occurring dimeric PSII
    intermediates from the cyanobacterium Thermosynechococcus vestitus at a resolution
    of about 2.2 Å. These intermediates contain inactive dimers lacking the oxygen-evolving
    complex (OEC) and semi-active dimers with the OEC present in one of the two monomers.
    Our structural data provide a mechanism for how assembly and disassembly of the
    Mn4CaO5 cluster is coordinated with the binding and release of the extrinsic proteins:
    restructuring of the C-terminal tail of D1 subunit during assembly or disassembly
    of the Mn cluster triggers conformational changes in D2, CP47 and CP43 to drive
    the binding/release of the extrinsic proteins. A combination of structural and
    mass spectrometry data also suggests that the inactive PSII complexes may include
    damaged complexes containing oxidized D1-His332, a monodentate ligand to one of
    the Mn ions of the OEC.@eng'
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Ziyu
      foaf_name: Zhao, Ziyu
      foaf_surname: Zhao
      foaf_workInfoHomepage: http://www.librecat.org/personId=a63fe682-9f3a-11ee-bf8c-cfdf919b9850
  - foaf_Person:
      foaf_givenName: Irene
      foaf_name: Vercellino, Irene
      foaf_surname: Vercellino
      foaf_workInfoHomepage: http://www.librecat.org/personId=3ED6AF16-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-5618-3449
  - foaf_Person:
      foaf_givenName: Julian P.
      foaf_name: Whitelegge, Julian P.
      foaf_surname: Whitelegge
  - foaf_Person:
      foaf_givenName: Karim
      foaf_name: Maghlaoui, Karim
      foaf_surname: Maghlaoui
  - foaf_Person:
      foaf_givenName: Wojciech
      foaf_name: Białek, Wojciech
      foaf_surname: Białek
  - foaf_Person:
      foaf_givenName: Peter J.
      foaf_name: Nixon, Peter J.
      foaf_surname: Nixon
  - foaf_Person:
      foaf_givenName: Leonid A
      foaf_name: Sazanov, Leonid A
      foaf_surname: Sazanov
      foaf_workInfoHomepage: http://www.librecat.org/personId=338D39FE-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-0977-7989
  bibo_doi: 10.1038/s41467-026-75324-x
  bibo_volume: 17
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2041-1723
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: Cryo-EM structures of naturally occurring dimeric photosystem II complexes
    lacking the Mn4CaO5 cluster@
  fabio_hasPubmedId: '42420307'
...