---
_id: '2277'
abstract:
- lang: eng
text: Redundancies and correlations in the responses of sensory neurons may seem
to waste neural resources, but they can also carry cues about structured stimuli
and may help the brain to correct for response errors. To investigate the effect
of stimulus structure on redundancy in retina, we measured simultaneous responses
from populations of retinal ganglion cells presented with natural and artificial
stimuli that varied greatly in correlation structure; these stimuli and recordings
are publicly available online. Responding to spatio-temporally structured stimuli
such as natural movies, pairs of ganglion cells were modestly more correlated
than in response to white noise checkerboards, but they were much less correlated
than predicted by a non-adapting functional model of retinal response. Meanwhile,
responding to stimuli with purely spatial correlations, pairs of ganglion cells
showed increased correlations consistent with a static, non-adapting receptive
field and nonlinearity. We found that in response to spatio-temporally correlated
stimuli, ganglion cells had faster temporal kernels and tended to have stronger
surrounds. These properties of individual cells, along with gain changes that
opposed changes in effective contrast at the ganglion cell input, largely explained
the pattern of pairwise correlations across stimuli where receptive field measurements
were possible.
article_number: e1003344
author:
- first_name: Kristina
full_name: Simmons, Kristina
last_name: Simmons
- first_name: Jason
full_name: Prentice, Jason
last_name: Prentice
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Jan
full_name: Homann, Jan
last_name: Homann
- first_name: Heather
full_name: Yee, Heather
last_name: Yee
- first_name: Stephanie
full_name: Palmer, Stephanie
last_name: Palmer
- first_name: Philip
full_name: Nelson, Philip
last_name: Nelson
- first_name: Vijay
full_name: Balasubramanian, Vijay
last_name: Balasubramanian
citation:
ama: Simmons K, Prentice J, Tkačik G, et al. Transformation of stimulus correlations
by the retina. PLoS Computational Biology. 2013;9(12). doi:10.1371/journal.pcbi.1003344
apa: Simmons, K., Prentice, J., Tkačik, G., Homann, J., Yee, H., Palmer, S., … Balasubramanian,
V. (2013). Transformation of stimulus correlations by the retina. PLoS Computational
Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1003344
chicago: Simmons, Kristina, Jason Prentice, Gašper Tkačik, Jan Homann, Heather Yee,
Stephanie Palmer, Philip Nelson, and Vijay Balasubramanian. “Transformation of
Stimulus Correlations by the Retina.” PLoS Computational Biology. Public
Library of Science, 2013. https://doi.org/10.1371/journal.pcbi.1003344.
ieee: K. Simmons et al., “Transformation of stimulus correlations by the
retina,” PLoS Computational Biology, vol. 9, no. 12. Public Library of
Science, 2013.
ista: Simmons K, Prentice J, Tkačik G, Homann J, Yee H, Palmer S, Nelson P, Balasubramanian
V. 2013. Transformation of stimulus correlations by the retina. PLoS Computational
Biology. 9(12), e1003344.
mla: Simmons, Kristina, et al. “Transformation of Stimulus Correlations by the Retina.”
PLoS Computational Biology, vol. 9, no. 12, e1003344, Public Library of
Science, 2013, doi:10.1371/journal.pcbi.1003344.
short: K. Simmons, J. Prentice, G. Tkačik, J. Homann, H. Yee, S. Palmer, P. Nelson,
V. Balasubramanian, PLoS Computational Biology 9 (2013).
date_created: 2018-12-11T11:56:43Z
date_published: 2013-12-05T00:00:00Z
date_updated: 2023-02-23T14:07:04Z
day: '05'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1003344
file:
- access_level: open_access
checksum: 46722afc4f7eabb0831165d9c1b171ad
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:36Z
date_updated: 2020-07-14T12:45:36Z
file_id: '5089'
file_name: IST-2016-410-v1+1_journal.pcbi.1003344.pdf
file_size: 3115568
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file_date_updated: 2020-07-14T12:45:36Z
has_accepted_license: '1'
intvolume: ' 9'
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
publist_id: '4667'
pubrep_id: '410'
quality_controlled: '1'
related_material:
record:
- id: '9752'
relation: research_data
status: public
scopus_import: 1
status: public
title: Transformation of stimulus correlations by the retina
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2013'
...