[{"abstract":[{"lang":"eng","text":"Auxin and calcium (Ca2+) are central plant signals that coordinate growth, development, and responses to environmental cues. Typically studied as largely parallel pathways, they are now increasingly recognized as interconnected networks whose activities converge at multiple regulatory levels. Recent advances in live imaging, biosensors, optogenetics, and structural approaches have revealed that auxin can rapidly trigger Ca2+ influx from the apoplast via TRANSPORT INHIBITOR RESPONSE1 (TIR1)/AUXIN-SIGNALING F-BOX (AFB)-dependent signaling mechanisms and Ca2+ channels, presumably involving cyclic nucleotides produced by TIR1/AFB auxin receptors. Conversely, Ca2+ signals arising from mechanosensing, wounding, and environmental stress can modulate auxin transport, signaling, and transcriptional outputs. Together, these discoveries highlight a dynamic, reciprocal signaling axis where Ca2+ acts both downstream and upstream of auxin to shape growth, development, tropisms, and regeneration."}],"das_tickbox":"0","publication_identifier":{"issn":["1360-1385"],"eissn":["1878-4372"]},"date_updated":"2026-09-17T07:42:27Z","researchdata_availability":"no","doi":"10.1016/j.tplants.2026.08.002","citation":{"short":"M. Zupunski, G. Grossmann, J. Friml, Trends in Plant Science (2026).","ama":"Zupunski M, Grossmann G, Friml J. Decoding dialog: The auxin–calcium signaling crosstalk in plants. <i>Trends in Plant Science</i>. 2026. doi:<a href=\"https://doi.org/10.1016/j.tplants.2026.08.002\">10.1016/j.tplants.2026.08.002</a>","chicago":"Zupunski, Milan, Guido Grossmann, and Jiří Friml. “Decoding Dialog: The Auxin–Calcium Signaling Crosstalk in Plants.” <i>Trends in Plant Science</i>. Cell Press, 2026. <a href=\"https://doi.org/10.1016/j.tplants.2026.08.002\">https://doi.org/10.1016/j.tplants.2026.08.002</a>.","ista":"Zupunski M, Grossmann G, Friml J. 2026. Decoding dialog: The auxin–calcium signaling crosstalk in plants. Trends in Plant Science.","ieee":"M. Zupunski, G. Grossmann, and J. Friml, “Decoding dialog: The auxin–calcium signaling crosstalk in plants,” <i>Trends in Plant Science</i>. Cell Press, 2026.","mla":"Zupunski, Milan, et al. “Decoding Dialog: The Auxin–Calcium Signaling Crosstalk in Plants.” <i>Trends in Plant Science</i>, Cell Press, 2026, doi:<a href=\"https://doi.org/10.1016/j.tplants.2026.08.002\">10.1016/j.tplants.2026.08.002</a>.","apa":"Zupunski, M., Grossmann, G., &#38; Friml, J. (2026). Decoding dialog: The auxin–calcium signaling crosstalk in plants. <i>Trends in Plant Science</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.tplants.2026.08.002\">https://doi.org/10.1016/j.tplants.2026.08.002</a>"},"pmid":1,"publisher":"Cell Press","external_id":{"pmid":["42692943"]},"publication":"Trends in Plant Science","corr_author":"1","title":"Decoding dialog: The auxin–calcium signaling crosstalk in plants","year":"2026","_id":"22927","language":[{"iso":"eng"}],"publication_status":"epub_ahead","day":"04","type":"journal_article","ddc":["580"],"date_created":"2026-09-13T22:01:56Z","oa":1,"date_published":"2026-09-04T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","license":"https://creativecommons.org/licenses/by/4.0/","status":"public","fulldoi":"https://doi.org/10.1016/j.tplants.2026.08.002","acknowledgement":"The authors would like to acknowledge many colleagues whose valuable contributions to the field could not be included in this review due to space limitations and reference constraints.","author":[{"id":"f6a21fce-573e-11f0-a150-a8d96aee2539","full_name":"Zupunski, Milan","last_name":"Zupunski","first_name":"Milan"},{"first_name":"Guido","last_name":"Grossmann","full_name":"Grossmann, Guido"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jiří","last_name":"Friml","full_name":"Friml, Jiří"}],"scopus_import":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.tplants.2026.08.002"}],"has_accepted_license":"1","month":"09","article_type":"original","OA_place":"publisher","quality_controlled":"1","OA_type":"hybrid","oa_version":"Published Version","department":[{"_id":"JiFr"}],"keyword":["auxin","calcium","rapid signaling","crosstalk","growth regulation","cyclic nucleotides"],"article_processing_charge":"No","supplementarymaterial":"no"}]