---
res:
  bibo_abstract:
  - The regulation of 3D cell shape is a fundamental problem of life. In multicellular
    tissues, cell shape emerges through the balance of forces inside and outside the
    cell. In epithelia, the basement membrane (BM) is the first extracellular barrier
    that cells sense biochemically and mechanically. Despite this, little is known
    about how BM mechanical properties are regulated and how they impact cell shape.
    Through mathematical modeling, we show that the stress relaxation time of the
    BM can regulate cell shape. Using molecular dynamics simulations, we show that
    the stress relaxation time of a collagen IV network can be inferred from the lifetime
    of collagen IV molecules. To measure collagen IV lifetime in vivo, we develop
    a fluorescent timer reporter for collagen IV and show that perlecan modifies collagen
    IV lifetime. This cross-disciplinary approach establishes a multiscale framework
    to probe matrix turnover, and its regulation and function in cell shape control.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Ricardo
      foaf_name: Barrientos, Ricardo
      foaf_surname: Barrientos
  - foaf_Person:
      foaf_givenName: Billie
      foaf_name: Meadowcroft, Billie
      foaf_surname: Meadowcroft
      foaf_workInfoHomepage: http://www.librecat.org/personId=a4725fd6-932b-11ed-81e2-c098c7f37ae1
    orcid: 0000-0003-3441-1337
  - foaf_Person:
      foaf_givenName: Besaiz J.
      foaf_name: Sánchez-Sánchez, Besaiz J.
      foaf_surname: Sánchez-Sánchez
  - foaf_Person:
      foaf_givenName: Brian M.
      foaf_name: Stramer, Brian M.
      foaf_surname: Stramer
  - foaf_Person:
      foaf_givenName: Ewa K.
      foaf_name: Paluch, Ewa K.
      foaf_surname: Paluch
  - foaf_Person:
      foaf_givenName: Guillaume
      foaf_name: Charras, Guillaume
      foaf_surname: Charras
  - foaf_Person:
      foaf_givenName: Shiladitya
      foaf_name: Banerjee, Shiladitya
      foaf_surname: Banerjee
  - foaf_Person:
      foaf_givenName: Anđela
      foaf_name: Šarić, Anđela
      foaf_surname: Šarić
      foaf_workInfoHomepage: http://www.librecat.org/personId=bf63d406-f056-11eb-b41d-f263a6566d8b
    orcid: 0000-0002-7854-2139
  - foaf_Person:
      foaf_givenName: Yanlan
      foaf_name: Mao, Yanlan
      foaf_surname: Mao
  bibo_doi: 10.1016/j.cell.2026.07.010
  bibo_issue: '18'
  bibo_volume: 189
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0092-8674
  - http://id.crossref.org/issn/1097-4172
  dct_language: eng
  dct_publisher: Elsevier@
  dct_title: Basement membrane turnover controls cell shape@
  fabio_hasPubmedId: '42532043'
...