article published yes Carla L Padilla Franzotti author Gabriel J Olguín-Orellana author Nicolas Palopoli author Sebastián Urquiza-Zurich author Adrian Garcia-Moreno author Sara Monzón author Mónica Cabrera-Pasadas author Irene Soler Sáez author Carla Perpiñá-Clérigues author Rafael J Puche Quiñonez author Jennifer Vélez Segura author Jose Abel Lovaco-Flores author Cleidy M Osorio Mogollón author Eva M Esquinas-Román author Maria C Miserendino author 273e0cbd-72f0-11ef-b75a-f9f932e292fa Pradeep Eranti author Ana Castillo-Orozco author Yesid Cuesta-Astroz author R Gonzalo Parra author PaSc department GradSch department Linguistic inequality remains a silent barrier in contemporary science, particularly in rapidly evolving and interdisciplinary fields such as bioinformatics. This article examines how the Spanish-speaking community has responded to this gap through the creation of the Simposio de Estudiantes Hispanohablantes de Bioinformática y Biología Computacional (SEH2Bioinfo), a collective initiative that transforms language into a tool for inclusion and collaboration. Drawing on a historical review of the use of Spanish in scientific communication and an analysis of the two editions of SEH2Bioinfo (2022 and 2025), complemented by surveys of more than 1500 participants, we explore the effects of language on confidence, participation, and academic visibility. The findings show that Spanish can serve as a space for training and mentorship without compromising rigor, while simultaneously strengthening international networks and promoting open science. The growth of SEH2Bioinfo, its collaborative approach, and its intercontinental reach establish the symposium as a model for linguistic equity in scientific practice. Its experience demonstrates that expanding linguistic diversity in bioinformatics is not only possible but essential to building a global scientific community that is fairer, more connected, and representative. https://research-explorer.ista.ac.at/download/22957/23016/2026_BioinformaticsAdvances_Franzotti.pdf application/pdfno Oxford University Press2026 eng 2635-0041 4257778310.1093/bioadv/vbag182 61 https://doi.org/10.1093/bioadv/vbag271 Padilla Franzotti CL, Olguín-Orellana GJ, Palopoli N, Urquiza-Zurich S, Garcia-Moreno A, Monzón S, Cabrera-Pasadas M, Soler Sáez I, Perpiñá-Clérigues C, Puche Quiñonez RJ, Vélez Segura J, Lovaco-Flores JA, Osorio Mogollón CM, Esquinas-Román EM, Miserendino MC, Eranti P, Castillo-Orozco A, Cuesta-Astroz Y, Parra RG. 2026. Bioinformatics in Español: Expanding open, diverse, and collaborative science through SEH2Bioinfo. Bioinformatics Advances. 6(1), vbag182. Padilla Franzotti, C. L., Olguín-Orellana, G. J., Palopoli, N., Urquiza-Zurich, S., Garcia-Moreno, A., Monzón, S., … Parra, R. G. (2026). Bioinformatics in Español: Expanding open, diverse, and collaborative science through SEH2Bioinfo. <i>Bioinformatics Advances</i>. Oxford University Press. <a href="https://doi.org/10.1093/bioadv/vbag182">https://doi.org/10.1093/bioadv/vbag182</a> Padilla Franzotti, Carla L., et al. “Bioinformatics in Español: Expanding Open, Diverse, and Collaborative Science through SEH2Bioinfo.” <i>Bioinformatics Advances</i>, vol. 6, no. 1, vbag182, Oxford University Press, 2026, doi:<a href="https://doi.org/10.1093/bioadv/vbag182">10.1093/bioadv/vbag182</a>. Padilla Franzotti CL, Olguín-Orellana GJ, Palopoli N, et al. Bioinformatics in Español: Expanding open, diverse, and collaborative science through SEH2Bioinfo. <i>Bioinformatics Advances</i>. 2026;6(1). doi:<a href="https://doi.org/10.1093/bioadv/vbag182">10.1093/bioadv/vbag182</a> C. L. Padilla Franzotti <i>et al.</i>, “Bioinformatics in Español: Expanding open, diverse, and collaborative science through SEH2Bioinfo,” <i>Bioinformatics Advances</i>, vol. 6, no. 1. Oxford University Press, 2026. Padilla Franzotti, Carla L, Gabriel J Olguín-Orellana, Nicolas Palopoli, Sebastián Urquiza-Zurich, Adrian Garcia-Moreno, Sara Monzón, Mónica Cabrera-Pasadas, et al. “Bioinformatics in Español: Expanding Open, Diverse, and Collaborative Science through SEH2Bioinfo.” <i>Bioinformatics Advances</i>. Oxford University Press, 2026. <a href="https://doi.org/10.1093/bioadv/vbag182">https://doi.org/10.1093/bioadv/vbag182</a>. C.L. Padilla Franzotti, G.J. Olguín-Orellana, N. Palopoli, S. Urquiza-Zurich, A. Garcia-Moreno, S. Monzón, M. Cabrera-Pasadas, I. Soler Sáez, C. Perpiñá-Clérigues, R.J. Puche Quiñonez, J. Vélez Segura, J.A. Lovaco-Flores, C.M. Osorio Mogollón, E.M. Esquinas-Román, M.C. Miserendino, P. Eranti, A. Castillo-Orozco, Y. Cuesta-Astroz, R.G. Parra, Bioinformatics Advances 6 (2026). 229572026-09-17T11:06:17Z2026-10-01T08:59:32Z