---
res:
  bibo_abstract:
  - The peripheral neural pathways that relay oral and post-ingestive chemo- and mechanosensory
    signals to the brain during food consumption are increasingly well understood.
    Far less is known about how these and other body signals are integrated and organized
    in the brainstem lateral parabrachial nucleus (LPBN), a key interoceptive sensory
    hub. We established methods for dense calcium imaging of 100s of neurons from
    mouse LPBN. Food consumption drove a seconds-long wave of activity across LPBN,
    with dynamics mirroring the movement of food through the upper gastrointestinal
    tract as observed using X-ray videofluoroscopy. By imaging the same neurons across
    days, we found that spatially clustered subsets of neurons encoded oral signals,
    stomach filling, visceral malaise, arousal, and/or body movement. Moreover, only
    certain subsets were modulated by cortical input. Together, these experiments
    establish a platform for understanding how peripheral and central interoceptive
    signals are integrated in the brainstem to guide behavior.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Rachel A.
      foaf_name: Essner, Rachel A.
      foaf_surname: Essner
  - foaf_Person:
      foaf_givenName: Kiersten
      foaf_name: Ruda, Kiersten
      foaf_surname: Ruda
  - foaf_Person:
      foaf_givenName: Hannah J.
      foaf_name: Choh, Hannah J.
      foaf_surname: Choh
  - foaf_Person:
      foaf_givenName: Hakan
      foaf_name: Kücükdereli, Hakan
      foaf_surname: Kücükdereli
      foaf_workInfoHomepage: http://www.librecat.org/personId=5d5f6ea4-ef9e-11f0-a10a-85e12a3552af
  - foaf_Person:
      foaf_givenName: Oren
      foaf_name: Amsalem, Oren
      foaf_surname: Amsalem
  - foaf_Person:
      foaf_givenName: Julia
      foaf_name: Edelhaus, Julia
      foaf_surname: Edelhaus
  - foaf_Person:
      foaf_givenName: Gracesenia
      foaf_name: Chahyadinata, Gracesenia
      foaf_surname: Chahyadinata
  - foaf_Person:
      foaf_givenName: Sverre
      foaf_name: Grødem, Sverre
      foaf_surname: Grødem
  - foaf_Person:
      foaf_givenName: Kristian K.
      foaf_name: Lensjø, Kristian K.
      foaf_surname: Lensjø
  - foaf_Person:
      foaf_givenName: Teresa E.
      foaf_name: Lever, Teresa E.
      foaf_surname: Lever
  - foaf_Person:
      foaf_givenName: Mark L.
      foaf_name: Andermann, Mark L.
      foaf_surname: Andermann
  bibo_doi: 10.1016/j.neuron.2026.08.015
  dct_date: 2026^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0896-6273
  - http://id.crossref.org/issn/1097-4199
  dct_language: eng
  dct_publisher: Cell Press@
  dct_title: Brainstem sensing of multiple body signals during food consumption@
  fabio_hasPubmedId: '42753729'
...