---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '23088'
abstract:
- lang: eng
  text: In this review, we provide an engineering assessment of prevalent blood-wetted
    cardiovascular devices, their hematologic complications, and their interconnections
    to identify key areas for future research. In fact, the incidence of cardiovascular
    diseases has promoted the development of various devices to treat these conditions,
    including mechanical circulatory supports (mechanical pumps that assist or replace
    failing hearts), artificial valves to replace faulty heart valves, stents to relieve
    obstructions in blood vessels, vascular grafts to repair/reconstruct damaged vessels,
    patches to reinforce or reconstruct cardiovascular tissues, and other implants.
    The hemocompatibility of these cardiovascular devices, namely their ability to
    interact with blood flow without causing adverse reactions, remains unsatisfactory,
    and recurrent complications include thrombosis, hemolysis, and bleeding. Therefore,
    the discussion provided herein will support readers approaching cardiovascular
    technologies in building a solid foundation and provide everyone with an up-to-date
    overview of ongoing research in this multidisciplinary field.
article_number: '167'
article_processing_charge: Yes
article_type: original
author:
- first_name: Damiano
  full_name: Padovani, Damiano
  last_name: Padovani
- first_name: Nasima S
  full_name: Afsharimani, Nasima S
  id: fe7df522-678a-11eb-9fb9-a37ecf42528e
  last_name: Afsharimani
- first_name: Andrea
  full_name: Cioncolini, Andrea
  last_name: Cioncolini
- first_name: Yu
  full_name: Ding, Yu
  last_name: Ding
citation:
  ama: Padovani D, Afsharimani NS, Cioncolini A, Ding Y. Hematologic complications
    and design challenges in cardiovascular devices. <i>Communications Engineering</i>.
    2026;5. doi:<a href="https://doi.org/10.1038/s44172-026-00771-9">10.1038/s44172-026-00771-9</a>
  apa: Padovani, D., Afsharimani, N. S., Cioncolini, A., &#38; Ding, Y. (2026). Hematologic
    complications and design challenges in cardiovascular devices. <i>Communications
    Engineering</i>. Springer Nature. <a href="https://doi.org/10.1038/s44172-026-00771-9">https://doi.org/10.1038/s44172-026-00771-9</a>
  chicago: Padovani, Damiano, Nasima S Afsharimani, Andrea Cioncolini, and Yu Ding.
    “Hematologic Complications and Design Challenges in Cardiovascular Devices.” <i>Communications
    Engineering</i>. Springer Nature, 2026. <a href="https://doi.org/10.1038/s44172-026-00771-9">https://doi.org/10.1038/s44172-026-00771-9</a>.
  ieee: D. Padovani, N. S. Afsharimani, A. Cioncolini, and Y. Ding, “Hematologic complications
    and design challenges in cardiovascular devices,” <i>Communications Engineering</i>,
    vol. 5. Springer Nature, 2026.
  ista: Padovani D, Afsharimani NS, Cioncolini A, Ding Y. 2026. Hematologic complications
    and design challenges in cardiovascular devices. Communications Engineering. 5,
    167.
  mla: Padovani, Damiano, et al. “Hematologic Complications and Design Challenges
    in Cardiovascular Devices.” <i>Communications Engineering</i>, vol. 5, 167, Springer
    Nature, 2026, doi:<a href="https://doi.org/10.1038/s44172-026-00771-9">10.1038/s44172-026-00771-9</a>.
  short: D. Padovani, N.S. Afsharimani, A. Cioncolini, Y. Ding, Communications Engineering
    5 (2026).
das_tickbox: '0'
date_created: 2026-10-11T22:02:04Z
date_published: 2026-09-30T00:00:00Z
date_updated: 2026-10-12T11:34:48Z
day: '30'
ddc:
- '570'
- '610'
department:
- _id: NanoFab
doi: 10.1038/s44172-026-00771-9
external_id:
  pmid:
  - '42816513'
file:
- access_level: open_access
  checksum: 770d3ef015bc3a8a81017f07a3225ab6
  content_type: application/pdf
  creator: dernst
  date_created: 2026-10-12T11:33:01Z
  date_updated: 2026-10-12T11:33:01Z
  file_id: '23108'
  file_name: 2026_CommunicationsEngineering_Padovani.pdf
  file_size: 9201511
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file_date_updated: 2026-10-12T11:33:01Z
fulldoi: https://doi.org/10.1038/s44172-026-00771-9
has_accepted_license: '1'
intvolume: '         5'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Communications Engineering
publication_identifier:
  eissn:
  - 2731-3395
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Hematologic complications and design challenges in cardiovascular devices
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2026'
...