---
res:
  bibo_abstract:
  - Roots must continuously adapt their growth and have evolved the ability to rapidly
    respond to diverse environmental and hormonal cues, including the phytohormone
    auxin. Auxin-induced cellular responses involve membrane depolarization, cytosolic
    calcium (Ca²⁺) elevation, and extracellular pH increase, but how these processes
    lead to rapid growth regulation remains unclear. Here, we show that cytosolic
    Ca²⁺ acts as a universal signal integrating diverse cues for rapid regulation
    of root growth. Using live imaging, microfluidics, and optogenetics in Arabidopsis,
    we demonstrate that a swift rise in cytosolic Ca²⁺ is the primary target of auxin
    signaling affecting growth inhibition. Disruption of Ca²⁺ influx abolishes these
    responses, whereas light-gated Ca²⁺ influx from the apoplast or endoplasmic reticulum
    stores inhibits growth. Multiple unrelated stimuli—including auxin, extracellular
    ATP, RALF peptides, and hydrogen peroxide—converge on this Ca²⁺-dependent mechanism.
    Cytosolic Ca²⁺ elevation thus represents a necessary and sufficient step for rapid
    growth inhibition, revealing a unifying principle of root signaling.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Marek
      foaf_name: Randuch, Marek
      foaf_surname: Randuch
      foaf_workInfoHomepage: http://www.librecat.org/personId=6ac4636d-15b2-11ec-abd3-fb8df79972ae
  - foaf_Person:
      foaf_givenName: Ivan
      foaf_name: Kulich, Ivan
      foaf_surname: Kulich
      foaf_workInfoHomepage: http://www.librecat.org/personId=57a1567c-8314-11eb-9063-c9ddc3451a54
  - foaf_Person:
      foaf_givenName: Dmitrii
      foaf_name: Vladimirtsev, Dmitrii
      foaf_surname: Vladimirtsev
      foaf_workInfoHomepage: http://www.librecat.org/personId=60466724-5355-11ee-ae5a-fa55e8f99c3d
  - foaf_Person:
      foaf_givenName: Shouguang
      foaf_name: Huang, Shouguang
      foaf_surname: Huang
  - foaf_Person:
      foaf_givenName: Rainer
      foaf_name: Hedrich, Rainer
      foaf_surname: Hedrich
  - foaf_Person:
      foaf_givenName: Jiří
      foaf_name: Friml, Jiří
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  bibo_doi: 10.1101/2025.10.17.683082
  dct_date: 2025^xs_gYear
  dct_language: eng
  dct_title: Cytosolic Ca2+ as a universal signal for rapid root growth regulation@
...