---
_id: '2455'
abstract:
- lang: eng
text: Local accumulation of the plant growth regulator auxin mediates pattern formation
in Arabidopsis roots and influences outgrowth and development of lateral root-
and shoot-derived primordia. However, it has remained unclear how auxin can simultaneously
regulate patterning and organ outgrowth and how its distribution is stabilized
in a primordium-specif ic manner. Here we show that five PIN genes collectively
control auxin distribution to regulate cell division and cell expansion in the
primary root. Furthermore, the joint action of these genes has an important role
in pattern formation by focusing the auxin maximum and restricting the expression
domain of PLETHORA (PLT) genes, major determinants for root stem cell specification.
In turn, PLT genes are required for PIN gene transcription to stabilize the auxin
maximum at the distal root tip. Our data reveal an interaction network of auxin
transport facilitators and root fate determinants that control patterning and
growth of the root primordium.
author:
- first_name: Ikram
full_name: Billou, Ikram
last_name: Billou
- first_name: Jian
full_name: Xu, Jian
last_name: Xu
- first_name: Marjolein
full_name: Wildwater, Marjolein
last_name: Wildwater
- first_name: Viola
full_name: Willemsen, Viola
last_name: Willemsen
- first_name: Ivan
full_name: Paponov, Ivan A
last_name: Paponov
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Renze
full_name: Heldstra, Renze
last_name: Heldstra
- first_name: Mitsuhiro
full_name: Aida, Mitsuhiro
last_name: Aida
- first_name: Klaus
full_name: Palme, Klaus J
last_name: Palme
- first_name: Ben
full_name: Scheres, Ben
last_name: Scheres
citation:
ama: Billou I, Xu J, Wildwater M, et al. The PIN auxin efflux facilitator network
controls growth and patterning in Arabidopsis roots. Nature. 2005;433(7021):39-44.
doi:10.1038/nature03184
apa: Billou, I., Xu, J., Wildwater, M., Willemsen, V., Paponov, I., Friml, J., …
Scheres, B. (2005). The PIN auxin efflux facilitator network controls growth and
patterning in Arabidopsis roots. Nature. Nature Publishing Group. https://doi.org/10.1038/nature03184
chicago: Billou, Ikram, Jian Xu, Marjolein Wildwater, Viola Willemsen, Ivan Paponov,
Jiří Friml, Renze Heldstra, Mitsuhiro Aida, Klaus Palme, and Ben Scheres. “The
PIN Auxin Efflux Facilitator Network Controls Growth and Patterning in Arabidopsis
Roots.” Nature. Nature Publishing Group, 2005. https://doi.org/10.1038/nature03184.
ieee: I. Billou et al., “The PIN auxin efflux facilitator network controls
growth and patterning in Arabidopsis roots,” Nature, vol. 433, no. 7021.
Nature Publishing Group, pp. 39–44, 2005.
ista: Billou I, Xu J, Wildwater M, Willemsen V, Paponov I, Friml J, Heldstra R,
Aida M, Palme K, Scheres B. 2005. The PIN auxin efflux facilitator network controls
growth and patterning in Arabidopsis roots. Nature. 433(7021), 39–44.
mla: Billou, Ikram, et al. “The PIN Auxin Efflux Facilitator Network Controls Growth
and Patterning in Arabidopsis Roots.” Nature, vol. 433, no. 7021, Nature
Publishing Group, 2005, pp. 39–44, doi:10.1038/nature03184.
short: I. Billou, J. Xu, M. Wildwater, V. Willemsen, I. Paponov, J. Friml, R. Heldstra,
M. Aida, K. Palme, B. Scheres, Nature 433 (2005) 39–44.
date_created: 2018-12-11T11:57:46Z
date_published: 2005-01-01T00:00:00Z
date_updated: 2021-01-12T06:57:35Z
day: '01'
doi: 10.1038/nature03184
extern: 1
intvolume: ' 433'
issue: '7021'
month: '01'
page: 39 - 44
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '4448'
quality_controlled: 0
status: public
title: The PIN auxin efflux facilitator network controls growth and patterning in
Arabidopsis roots
type: journal_article
volume: 433
year: '2005'
...