--- _id: '2455' abstract: - lang: eng text: Local accumulation of the plant growth regulator auxin mediates pattern formation in Arabidopsis roots and influences outgrowth and development of lateral root- and shoot-derived primordia. However, it has remained unclear how auxin can simultaneously regulate patterning and organ outgrowth and how its distribution is stabilized in a primordium-specif ic manner. Here we show that five PIN genes collectively control auxin distribution to regulate cell division and cell expansion in the primary root. Furthermore, the joint action of these genes has an important role in pattern formation by focusing the auxin maximum and restricting the expression domain of PLETHORA (PLT) genes, major determinants for root stem cell specification. In turn, PLT genes are required for PIN gene transcription to stabilize the auxin maximum at the distal root tip. Our data reveal an interaction network of auxin transport facilitators and root fate determinants that control patterning and growth of the root primordium. author: - first_name: Ikram full_name: Billou, Ikram last_name: Billou - first_name: Jian full_name: Xu, Jian last_name: Xu - first_name: Marjolein full_name: Wildwater, Marjolein last_name: Wildwater - first_name: Viola full_name: Willemsen, Viola last_name: Willemsen - first_name: Ivan full_name: Paponov, Ivan A last_name: Paponov - first_name: Jirí full_name: Jirí Friml id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Renze full_name: Heldstra, Renze last_name: Heldstra - first_name: Mitsuhiro full_name: Aida, Mitsuhiro last_name: Aida - first_name: Klaus full_name: Palme, Klaus J last_name: Palme - first_name: Ben full_name: Scheres, Ben last_name: Scheres citation: ama: Billou I, Xu J, Wildwater M, et al. The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots. Nature. 2005;433(7021):39-44. doi:10.1038/nature03184 apa: Billou, I., Xu, J., Wildwater, M., Willemsen, V., Paponov, I., Friml, J., … Scheres, B. (2005). The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots. Nature. Nature Publishing Group. https://doi.org/10.1038/nature03184 chicago: Billou, Ikram, Jian Xu, Marjolein Wildwater, Viola Willemsen, Ivan Paponov, Jiří Friml, Renze Heldstra, Mitsuhiro Aida, Klaus Palme, and Ben Scheres. “The PIN Auxin Efflux Facilitator Network Controls Growth and Patterning in Arabidopsis Roots.” Nature. Nature Publishing Group, 2005. https://doi.org/10.1038/nature03184. ieee: I. Billou et al., “The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots,” Nature, vol. 433, no. 7021. Nature Publishing Group, pp. 39–44, 2005. ista: Billou I, Xu J, Wildwater M, Willemsen V, Paponov I, Friml J, Heldstra R, Aida M, Palme K, Scheres B. 2005. The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots. Nature. 433(7021), 39–44. mla: Billou, Ikram, et al. “The PIN Auxin Efflux Facilitator Network Controls Growth and Patterning in Arabidopsis Roots.” Nature, vol. 433, no. 7021, Nature Publishing Group, 2005, pp. 39–44, doi:10.1038/nature03184. short: I. Billou, J. Xu, M. Wildwater, V. Willemsen, I. Paponov, J. Friml, R. Heldstra, M. Aida, K. Palme, B. Scheres, Nature 433 (2005) 39–44. date_created: 2018-12-11T11:57:46Z date_published: 2005-01-01T00:00:00Z date_updated: 2021-01-12T06:57:35Z day: '01' doi: 10.1038/nature03184 extern: 1 intvolume: ' 433' issue: '7021' month: '01' page: 39 - 44 publication: Nature publication_status: published publisher: Nature Publishing Group publist_id: '4448' quality_controlled: 0 status: public title: The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots type: journal_article volume: 433 year: '2005' ...