Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody Neki, Akio Ohishi, Hitoshi Kaneko, Takeshi Shigemoto, Ryuichi ; https://orcid.org/0000-0001-8761-9444 Nakanishi, Shigetada Mizuno, Noboru A monoclonal antibody against a metabotropic glutamate receptor, mGluR2, was produced by using a glutathione S-transferase (GST) fusion protein containing an N-terminal sequence of rat mGluR2. Intense mGluR2-like immunoreactivity (mGluR2-LI) was seen mainly in neuropil of the cerebral cortical regions, hippocampus, olfactory bulb, some diencephalic nuclei, dorsal cochlear nucleus and cerebellar cortex. In the cerebellar cortex, mGluR2-LI was seen only in Golgi cells. In Ammon's hem, mGluR2-LI was marked in the stratum lucidum of CA3 and the stratum lacunosum-moleculare of CA1-CA3, but not detected in the stratum pyramidale. The results indicate that mGluR2 is located not only presynaptically but also postsynaptically. Elsevier 1996 info:eu-repo/semantics/article doc-type:article text http://purl.org/coar/resource_type/c_2df8fbb1 https://research-explorer.ista.ac.at/record/2562 Neki A, Ohishi H, Kaneko T, Shigemoto R, Nakanishi S, Mizuno N. Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody. <i>Neuroscience Letters</i>. 1996;202(3):197-200. doi:<a href="https://doi.org/10.1016/0304-3940(95)12248-6">10.1016/0304-3940(95)12248-6</a> eng info:eu-repo/semantics/altIdentifier/doi/10.1016/0304-3940(95)12248-6 info:eu-repo/semantics/altIdentifier/issn/0304-3940 info:eu-repo/semantics/altIdentifier/pmid/8848265 info:eu-repo/semantics/closedAccess