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<titleInfo><title>Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody</title></titleInfo>


<note type="publicationStatus">published</note>


<note type="qualityControlled">yes</note>

<name type="personal">
  <namePart type="given">Akio</namePart>
  <namePart type="family">Neki</namePart>
  <role><roleTerm type="text">author</roleTerm> </role></name>
<name type="personal">
  <namePart type="given">Hitoshi</namePart>
  <namePart type="family">Ohishi</namePart>
  <role><roleTerm type="text">author</roleTerm> </role></name>
<name type="personal">
  <namePart type="given">Takeshi</namePart>
  <namePart type="family">Kaneko</namePart>
  <role><roleTerm type="text">author</roleTerm> </role></name>
<name type="personal">
  <namePart type="given">Ryuichi</namePart>
  <namePart type="family">Shigemoto</namePart>
  <role><roleTerm type="text">author</roleTerm> </role><identifier type="local">499F3ABC-F248-11E8-B48F-1D18A9856A87</identifier><description xsi:type="identifierDefinition" type="orcid">0000-0001-8761-9444</description></name>
<name type="personal">
  <namePart type="given">Shigetada</namePart>
  <namePart type="family">Nakanishi</namePart>
  <role><roleTerm type="text">author</roleTerm> </role></name>
<name type="personal">
  <namePart type="given">Noboru</namePart>
  <namePart type="family">Mizuno</namePart>
  <role><roleTerm type="text">author</roleTerm> </role></name>














<abstract lang="eng">A monoclonal antibody against a metabotropic glutamate receptor, mGluR2, was produced by using a glutathione S-transferase (GST) fusion protein containing an N-terminal sequence of rat mGluR2. Intense mGluR2-like immunoreactivity (mGluR2-LI) was seen mainly in neuropil of the cerebral cortical regions, hippocampus, olfactory bulb, some diencephalic nuclei, dorsal cochlear nucleus and cerebellar cortex. In the cerebellar cortex, mGluR2-LI was seen only in Golgi cells. In Ammon&apos;s hem, mGluR2-LI was marked in the stratum lucidum of CA3 and the stratum lacunosum-moleculare of CA1-CA3, but not detected in the stratum pyramidale. The results indicate that mGluR2 is located not only presynaptically but also postsynaptically.</abstract>

<originInfo><publisher>Elsevier</publisher><dateIssued encoding="w3cdtf">1996</dateIssued>
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<language><languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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<relatedItem type="host"><titleInfo><title>Neuroscience Letters</title></titleInfo>
  <identifier type="issn">0304-3940</identifier>
  <identifier type="MEDLINE">8848265</identifier><identifier type="doi">10.1016/0304-3940(95)12248-6</identifier>
<part><detail type="volume"><number>202</number></detail><detail type="issue"><number>3</number></detail><extent unit="pages">197 - 200</extent>
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<bibliographicCitation>
<ista>Neki A, Ohishi H, Kaneko T, Shigemoto R, Nakanishi S, Mizuno N. 1996. Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody. Neuroscience Letters. 202(3), 197–200.</ista>
<apa>Neki, A., Ohishi, H., Kaneko, T., Shigemoto, R., Nakanishi, S., &amp;#38; Mizuno, N. (1996). Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody. &lt;i&gt;Neuroscience Letters&lt;/i&gt;. Elsevier. &lt;a href=&quot;https://doi.org/10.1016/0304-3940(95)12248-6&quot;&gt;https://doi.org/10.1016/0304-3940(95)12248-6&lt;/a&gt;</apa>
<ieee>A. Neki, H. Ohishi, T. Kaneko, R. Shigemoto, S. Nakanishi, and N. Mizuno, “Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody,” &lt;i&gt;Neuroscience Letters&lt;/i&gt;, vol. 202, no. 3. Elsevier, pp. 197–200, 1996.</ieee>
<chicago>Neki, Akio, Hitoshi Ohishi, Takeshi Kaneko, Ryuichi Shigemoto, Shigetada Nakanishi, and Noboru Mizuno. “Pre- and Postsynaptic Localization of a Metabotropic Glutamate Receptor, MGluR2, in the Rat Brain: An Immunohistochemical Study with a Monoclonal Antibody.” &lt;i&gt;Neuroscience Letters&lt;/i&gt;. Elsevier, 1996. &lt;a href=&quot;https://doi.org/10.1016/0304-3940(95)12248-6&quot;&gt;https://doi.org/10.1016/0304-3940(95)12248-6&lt;/a&gt;.</chicago>
<mla>Neki, Akio, et al. “Pre- and Postsynaptic Localization of a Metabotropic Glutamate Receptor, MGluR2, in the Rat Brain: An Immunohistochemical Study with a Monoclonal Antibody.” &lt;i&gt;Neuroscience Letters&lt;/i&gt;, vol. 202, no. 3, Elsevier, 1996, pp. 197–200, doi:&lt;a href=&quot;https://doi.org/10.1016/0304-3940(95)12248-6&quot;&gt;10.1016/0304-3940(95)12248-6&lt;/a&gt;.</mla>
<ama>Neki A, Ohishi H, Kaneko T, Shigemoto R, Nakanishi S, Mizuno N. Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody. &lt;i&gt;Neuroscience Letters&lt;/i&gt;. 1996;202(3):197-200. doi:&lt;a href=&quot;https://doi.org/10.1016/0304-3940(95)12248-6&quot;&gt;10.1016/0304-3940(95)12248-6&lt;/a&gt;</ama>
<short>A. Neki, H. Ohishi, T. Kaneko, R. Shigemoto, S. Nakanishi, N. Mizuno, Neuroscience Letters 202 (1996) 197–200.</short>
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