---
res:
  bibo_abstract:
  - Glutamate receptors have been linked to the regulation of several developmental
    events in the CNS. By using cortical slices of early postnatal mice, we show that
    in layer I cells, glutamate produces intracellular calcium ([Ca2+]i) elevations
    mediated by ionotropic and metabotropic glutamate receptors (mGluRs). The contribution
    of mGluRs to these responses was demonstrated by application of tACPD, an agonist
    to groups I and II mGluRs, which evoked [Ca2+]i increases that could be reversibly
    blocked by MCPG, an antagonist to groups I and II mGluRs. In the absence of extracellular
    Ca2+, repetitive applications of tACPD or quisqualate, an agonist to group I mGluRs,
    elicited decreasing [Ca2+]i responses that were restored by refilling a thapsigargin-sensitive
    Ca2+ store. The use of specific group I mGluR agonists CHPG and DHPG indicated
    that the functional mGluR in layer I was of the mGluR1 subtype. Subtype specific
    antibodies confirmed the presence of mGlur1α, but not mGluR5, in Cajal-Retzius
    (Reelin-immunoreactive) neurons.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Galán
      foaf_name: Martínez, Galán
      foaf_surname: Martínez
  - foaf_Person:
      foaf_givenName: Guillermina
      foaf_name: López Bendito, Guillermina
      foaf_surname: López Bendito
  - foaf_Person:
      foaf_givenName: Rafael
      foaf_name: Luján, Rafael
      foaf_surname: Luján
  - foaf_Person:
      foaf_givenName: Ryuichi
      foaf_name: Shigemoto, Ryuichi
      foaf_surname: Shigemoto
      foaf_workInfoHomepage: http://www.librecat.org/personId=499F3ABC-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8761-9444
  - foaf_Person:
      foaf_givenName: Alfonso
      foaf_name: Fairén, Alfonso
      foaf_surname: Fairén
  - foaf_Person:
      foaf_givenName: Miguel
      foaf_name: Valdeolmillos, Miguel
      foaf_surname: Valdeolmillos
  bibo_doi: 10.1046/j.0953-816X.2001.01494.x
  bibo_issue: '6'
  bibo_volume: 13
  dct_date: 2001^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0953-816X
  dct_language: eng
  dct_publisher: Wiley-Blackwell@
  dct_title: Cajal-Retzius cells in early postnatal mouse cortex selectively express
    functional metabotropic glutamate receptors@
  fabio_hasPubmedId: '11285012'
...