---
res:
  bibo_abstract:
  - The release of glutamate and GABA is modulated by presynaptic metabotropic glutamate
    receptors (mGluRs). We used immunocytochemical methods to define the location
    of the group III receptor mGluR7a in glutamatergic and GABAergic terminals innervating
    GABAergic interneurons and pyramidal cells. Immunoreactivity for mGluR7a was localized
    in the presynaptic active zone of both identified GABAergic and presumed glutamatergic
    terminals. Terminals innervating dendritic spines showed a variable level of receptor
    immunoreactivity, ranging from immunonegative to strongly immunopositive. The
    frequency of strongly mGluR7a positive terminals innervating the soma and dendrites
    of mGluR1α/somatostatin-expressing interneurons was very high relative to other
    neurons. On dendrites that received mGluR7a-enriched glutamatergic innervation,
    at least 80% of GABAergic terminals were immunopositive for mGluR7a. On such dendrites
    virtually all (95%) vasoactive intestinal polypeptide (VIP) positive (GABAergic)
    terminals were enriched in mGluR7a. The targets of VIP/mGluR7a-expressing terminals
    were mainly (88%) mGluR1α-expressing interneurons, which were mostly somatostatin
    immunopositive. Parvalbumin positive terminals were immunonegative for mGluR7a.
    Some parvalbumin immunoreactive dendrites received strongly mGluR7a positive terminals.
    The subcellular location, as well as the cell type and synapse-specific distribution
    of mGluR7a in isocortical neuronal circuits, is homologous to its distribution
    in the hippocampus. The specific location of mGluR7a in the presynaptic active
    zone of both glutamatergic and GABAergic synapses may be related to the proximity
    of calcium channels and the vesicle fusion machinery. The enrichment of mGluR7a
    in the main GABAergic, as well as in the glutamatergic, innervation of mGluR1α/somatostatin-expressing
    interneurons suggests that their activation is under unique regulation by extracellular
    glutamate.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Yannis
      foaf_name: Dalezios, Yannis
      foaf_surname: Dalezios
  - foaf_Person:
      foaf_givenName: Rafael
      foaf_name: Luján, Rafael
      foaf_surname: Luján
  - foaf_Person:
      foaf_givenName: Ryuichi
      foaf_name: Shigemoto, Ryuichi
      foaf_surname: Shigemoto
      foaf_workInfoHomepage: http://www.librecat.org/personId=499F3ABC-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8761-9444
  - foaf_Person:
      foaf_givenName: John
      foaf_name: Roberts, John
      foaf_surname: Roberts
  - foaf_Person:
      foaf_givenName: Péter
      foaf_name: Somogyi, Péter
      foaf_surname: Somogyi
  bibo_doi: 10.1093/cercor/12.9.961
  bibo_issue: '9'
  bibo_volume: 12
  dct_date: 2002^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1047-3211
  dct_language: eng
  dct_publisher: Oxford University Press@
  dct_title: Enrichment of mGluR7a in the Presynaptic active zones of GABAergic and
    Non-GABAergic terminals on interneurons in the rat somatosensory cortex@
  fabio_hasPubmedId: '12183395'
...