---
res:
  bibo_abstract:
  - In the hippocampal CA1 region, metabotropic glutamate subtype 1 (mGluR1) receptors
    have been implicated in a variety of physiological responses to glutamate, which
    include modulation of synaptic transmission and plasticity, as well as neuronal
    excitability and synchronization. The mGluR1α isoform is characteristically expressed
    only by nonprincipal cells, and it is particularly enriched in somatostatin (SS
    -containing interneurons in stratum oriens-alveus. Anatomical and physiological
    data have indicated the presence of mGluR1α in several distinct classes of interneurons
    with their somata located also in strata pyramidale, radiatum, and lacunosum moleculare.
    Each different interneuron subtype, as defined by functionally relevant criteria,
    including input/output characteristics and expression of selective molecular markers,
    subserves distinct functions in local hippocampal circuits. We have investigated
    which of the different CA1 interneuron classes express mGluR1α by immunofluorescent
    labeling, combining antibodies to mGluR1α, calcium-binding proteins, and neuropeptides,
    and by intracellular labeling in vitro. Several types of interneuron that are
    immunopositive for mGluR1α each targeted different domains of pyramidal cells
    and included (1) O-LM interneurons, found to coexpress both SS and parvalbumin
    (PV); (2) interneurons with target selectivity for other interneurons, expressing
    vasoactive intestinal polypeptide (VIP) and/or the calcium-binding protein calretinin;
    (3) procholecystokinin-immunopositive interneurons probably non-basket and dendrite-targeting;
    and (4) an as-yet unidentified SS-immunoreactive but PV-immunonegative interneuron
    class, possibly corresponding to oriensbistratified cells. Estimation of the relative
    proportion of mGluR1α-positive interneurons showed 43%, 46%, and 30% co-labeling
    with SS, VIP, or PV, respectively. The identification of the specific subclasses
    of CA1 interneurons expressing mGluR1α provides the network basis for assessing
    the contribution of this receptor to the excitability of the hippocampus.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Francesco
      foaf_name: Ferraguti, Francesco
      foaf_surname: Ferraguti
  - foaf_Person:
      foaf_givenName: Philip
      foaf_name: Cobden, Philip M
      foaf_surname: Cobden
  - foaf_Person:
      foaf_givenName: Marie
      foaf_name: Pollard, Marie
      foaf_surname: Pollard
  - foaf_Person:
      foaf_givenName: David
      foaf_name: Cope, David W
      foaf_surname: Cope
  - foaf_Person:
      foaf_givenName: Ryuichi
      foaf_name: Ryuichi Shigemoto
      foaf_surname: Shigemoto
      foaf_workInfoHomepage: http://www.librecat.org/personId=499F3ABC-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8761-9444
  - foaf_Person:
      foaf_givenName: Masahiko
      foaf_name: Watanabe, Masahiko
      foaf_surname: Watanabe
  - foaf_Person:
      foaf_givenName: Péter
      foaf_name: Somogyi, Péter
      foaf_surname: Somogyi
  bibo_doi: 10.1002/hipo.10163
  bibo_issue: '2'
  bibo_volume: 14
  dct_date: 2004^xs_gYear
  dct_publisher: Wiley-Blackwell@
  dct_title: Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in
    distinct classes of interneuron in the CA1 region of the rat hippocampus@
...