{"quality_controlled":0,"month":"04","intvolume":"         3","author":[{"last_name":"Kawakami","first_name":"Ryosuke","full_name":"Kawakami, Ryosuke"},{"last_name":"Dobi","first_name":"Alice","full_name":"Dobi, Alice"},{"last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444"},{"first_name":"Isao","full_name":"Ito, Isao","last_name":"Ito"}],"publication_status":"published","publist_id":"4222","publisher":"Public Library of Science","issue":"4","date_published":"2008-04-16T00:00:00Z","abstract":[{"lang":"eng","text":"Left-right (L-R) asymmetry is a fundamental feature of higher-order neural function. However, the molecular basis of brain asymmetry remains unclear. We recently reported L-R asymmetry of hippocampal circuitry caused by differential allocation of N-methyl-O-aspartate receptor (NMDAR) subunit GluRε2 (NR2B) in hippocambal synapses. Using electrophysiology and immunocytochemistry, here we analyzed the hippocampal circuitry of the inversus viscerum (iv) mouse that has a randomized laterality of internal organs. The iv mouse hippocampus lacks L-R asymmetry, it exhibits right isomerism in the synaptic distribution of the ε2 subunit, irrespective of the laterality of visceral organs. This independent right isomerism of the hippocampus is the first evidence that a distinct mechanism downstream of the iv mutation generates brain asymmetry."}],"date_created":"2018-12-11T11:59:00Z","date_updated":"2021-01-12T06:58:59Z","doi":"10.1371/journal.pone.0001945","title":"Right isomerism of the brain in inversus viscerum mutant mice","volume":3,"extern":1,"year":"2008","status":"public","publication":"PLoS One","_id":"2676","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","citation":{"short":"R. Kawakami, A. Dobi, R. Shigemoto, I. Ito, PLoS One 3 (2008).","ama":"Kawakami R, Dobi A, Shigemoto R, Ito I. Right isomerism of the brain in inversus viscerum mutant mice. <i>PLoS One</i>. 2008;3(4). doi:<a href=\"https://doi.org/10.1371/journal.pone.0001945\">10.1371/journal.pone.0001945</a>","mla":"Kawakami, Ryosuke, et al. “Right Isomerism of the Brain in Inversus Viscerum Mutant Mice.” <i>PLoS One</i>, vol. 3, no. 4, Public Library of Science, 2008, doi:<a href=\"https://doi.org/10.1371/journal.pone.0001945\">10.1371/journal.pone.0001945</a>.","ieee":"R. Kawakami, A. Dobi, R. Shigemoto, and I. Ito, “Right isomerism of the brain in inversus viscerum mutant mice,” <i>PLoS One</i>, vol. 3, no. 4. Public Library of Science, 2008.","apa":"Kawakami, R., Dobi, A., Shigemoto, R., &#38; Ito, I. (2008). Right isomerism of the brain in inversus viscerum mutant mice. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0001945\">https://doi.org/10.1371/journal.pone.0001945</a>","ista":"Kawakami R, Dobi A, Shigemoto R, Ito I. 2008. Right isomerism of the brain in inversus viscerum mutant mice. PLoS One. 3(4).","chicago":"Kawakami, Ryosuke, Alice Dobi, Ryuichi Shigemoto, and Isao Ito. “Right Isomerism of the Brain in Inversus Viscerum Mutant Mice.” <i>PLoS One</i>. Public Library of Science, 2008. <a href=\"https://doi.org/10.1371/journal.pone.0001945\">https://doi.org/10.1371/journal.pone.0001945</a>."},"day":"16"}