--- _id: '2835' abstract: - lang: eng text: The phytohormone auxin regulates virtually every aspect of plant development. To identify new genes involved in auxin activity, a genetic screen was performed for Arabidopsis (Arabidopsis thaliana) mutants with altered expression of the auxin-responsive reporter DR5rev:GFP. One of the mutants recovered in the screen, designated as weak auxin response3 (wxr3), exhibits much lower DR5rev:GFP expression when treated with the synthetic auxin 2,4-dichlorophenoxyacetic acid and displays severe defects in root development. The wxr3 mutant decreases polar auxin transport and results in a disruption of the asymmetric auxin distribution. The levels of the auxin transporters AUXIN1 and PIN-FORMED are dramatically reduced in the wxr3 root tip. Molecular analyses demonstrate that WXR3 is ROOT ULTRAVIOLET B-SENSITIVE1 (RUS1), a member of the conserved Domain of Unknown Function647 protein family found in diverse eukaryotic organisms. Our data suggest that RUS1/WXR3 plays an essential role in the regulation of polar auxin transport by maintaining the proper level of auxin transporters on the plasma membrane. author: - first_name: Hong full_name: Yu, Hong last_name: Yu - first_name: Michael full_name: Karampelias, Michael last_name: Karampelias - first_name: Stéphanie full_name: Robert, Stéphanie last_name: Robert - first_name: Wendy full_name: Peer, Wendy last_name: Peer - first_name: Ranjan full_name: Swarup, Ranjan last_name: Swarup - first_name: Songqing full_name: Ye, Songqing last_name: Ye - first_name: Lei full_name: Ge, Lei last_name: Ge - first_name: Jerry full_name: Cohen, Jerry last_name: Cohen - first_name: Angus full_name: Murphy, Angus last_name: Murphy - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Mark full_name: Estelle, Mark last_name: Estelle citation: ama: Yu H, Karampelias M, Robert S, et al. Root ultraviolet b-sensitive1/weak auxin response3 is essential for polar auxin transport in arabidopsis. Plant Physiology. 2013;162(2):965-976. doi:10.1104/pp.113.217018 apa: Yu, H., Karampelias, M., Robert, S., Peer, W., Swarup, R., Ye, S., … Estelle, M. (2013). Root ultraviolet b-sensitive1/weak auxin response3 is essential for polar auxin transport in arabidopsis. Plant Physiology. American Society of Plant Biologists. https://doi.org/10.1104/pp.113.217018 chicago: Yu, Hong, Michael Karampelias, Stéphanie Robert, Wendy Peer, Ranjan Swarup, Songqing Ye, Lei Ge, et al. “Root Ultraviolet B-Sensitive1/Weak Auxin Response3 Is Essential for Polar Auxin Transport in Arabidopsis.” Plant Physiology. American Society of Plant Biologists, 2013. https://doi.org/10.1104/pp.113.217018. ieee: H. Yu et al., “Root ultraviolet b-sensitive1/weak auxin response3 is essential for polar auxin transport in arabidopsis,” Plant Physiology, vol. 162, no. 2. American Society of Plant Biologists, pp. 965–976, 2013. ista: Yu H, Karampelias M, Robert S, Peer W, Swarup R, Ye S, Ge L, Cohen J, Murphy A, Friml J, Estelle M. 2013. Root ultraviolet b-sensitive1/weak auxin response3 is essential for polar auxin transport in arabidopsis. Plant Physiology. 162(2), 965–976. mla: Yu, Hong, et al. “Root Ultraviolet B-Sensitive1/Weak Auxin Response3 Is Essential for Polar Auxin Transport in Arabidopsis.” Plant Physiology, vol. 162, no. 2, American Society of Plant Biologists, 2013, pp. 965–76, doi:10.1104/pp.113.217018. short: H. Yu, M. Karampelias, S. Robert, W. Peer, R. Swarup, S. Ye, L. Ge, J. Cohen, A. Murphy, J. Friml, M. Estelle, Plant Physiology 162 (2013) 965–976. date_created: 2018-12-11T11:59:51Z date_published: 2013-06-01T00:00:00Z date_updated: 2021-01-12T07:00:05Z day: '01' department: - _id: JiFr doi: 10.1104/pp.113.217018 external_id: pmid: - '23580592' intvolume: ' 162' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668084/ month: '06' oa: 1 oa_version: Submitted Version page: 965 - 976 pmid: 1 publication: Plant Physiology publication_status: published publisher: American Society of Plant Biologists publist_id: '3964' quality_controlled: '1' scopus_import: 1 status: public title: Root ultraviolet b-sensitive1/weak auxin response3 is essential for polar auxin transport in arabidopsis type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 162 year: '2013' ...