--- res: bibo_abstract: - 'Retina is a paradigmatic system for studying sensory encoding: the transformation of light into spiking activity of ganglion cells. The inverse problem, where stimulus is reconstructed from spikes, has received less attention, especially for complex stimuli that should be reconstructed “pixel-by-pixel”. We recorded around a hundred neurons from a dense patch in a rat retina and decoded movies of multiple small randomly-moving discs. We constructed nonlinear (kernelized and neural network) decoders that improved significantly over linear results. An important contribution to this was the ability of nonlinear decoders to reliably separate between neural responses driven by locally fluctuating light signals, and responses at locally constant light driven by spontaneous-like activity. This improvement crucially depended on the precise, non-Poisson temporal structure of individual spike trains, which originated in the spike-history dependence of neural responses. We propose a general principle by which downstream circuitry could discriminate between spontaneous and stimulus-driven activity based solely on higher-order statistical structure in the incoming spike trains.@eng' bibo_authorlist: - foaf_Person: foaf_givenName: Vicent foaf_name: Botella Soler, Vicent foaf_surname: Botella Soler foaf_workInfoHomepage: http://www.librecat.org/personId=421234E8-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0002-8790-1914 - foaf_Person: foaf_givenName: Stephane foaf_name: Deny, Stephane foaf_surname: Deny - foaf_Person: foaf_givenName: Georg S foaf_name: Martius, Georg S foaf_surname: Martius - foaf_Person: foaf_givenName: Olivier foaf_name: Marre, Olivier foaf_surname: Marre - foaf_Person: foaf_givenName: Gasper foaf_name: Tkacik, Gasper foaf_surname: Tkacik foaf_workInfoHomepage: http://www.librecat.org/personId=3D494DCA-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0002-6699-1455 bibo_doi: 10.1371/journal.pcbi.1006057 bibo_issue: '5' bibo_volume: 14 dct_date: 2018^xs_gYear dct_identifier: - UT:000434012100002 dct_language: eng dct_publisher: Public Library of Science@ dct_title: Nonlinear decoding of a complex movie from the mammalian retina@ ...