TY - JOUR AB - Polar flow of the phytohormone auxin requires plasma membrane‐associated PIN proteins and underlies multiple developmental processes in plants. Here we address the importance of the polarity of subcellular PIN localization for the directionality of auxin transport in Arabidopsis thaliana. Expression of different PINs in the root epidermis revealed the importance of PIN polar positions for directional auxin flow and root gravitropic growth. Interfering with sequence-embedded polarity signals directly demonstrates that PIN polarity is a primary factor in determining the direction of auxin flow in meristematic tissues. This finding provides a crucial piece in the puzzle of how auxin flow can be redirected via rapid changes in PIN polarity. AU - Wiśniewska, Justyna AU - Xu, Jian AU - Seifertová, Daniela AU - Brewer, Philip B AU - Růžička, Kamil AU - Blilou, Ikram AU - Rouquié, David AU - Eva Benková AU - Scheres, Ben AU - Jirí Friml ID - 3011 IS - 5775 JF - Science TI - Polar PIN localization directs auxin flow in plants VL - 312 ER -