---
_id: '3021'
abstract:
- lang: eng
  text: Polarized transport of the plant hormone auxin influences multiple growth
    processes in plants and is regulated by plasma-membrane-localized efflux and uptake
    carriers. The PGP (P-glycoprotein) ABC transporters (ATP-binding-cassette transporters),
    PIN (pin-formed) subfamily of major facilitator proteins and members of AUX/LAX
    families have been shown to independently transport auxin both in planta and in
    heterologous systems. However, PIN- and PGP-mediated transport in heterologous
    systems exhibits decreased substrate specificity and inhibitor-sensitivity compared
    with what is seen in plants and plant cells. To determine whether PIN-PGP interactions
    enhance transport specificity, we analysed interactions of the representative
    auxin-transporting PGPs with PIN1 and AUX1 in planta and in heterologous systems.
    Here, we provide evidence that PINs and PGPs interact and function both independently
    and co-ordinately to control polar auxin transport and impart transport specificity
    and directionality. These interactions take place in protein complexes stabilized
    by PGPs in detergent-resistant microdomains.
alternative_title:
- Biochemical Society Transactions
author:
- first_name: Anindita
  full_name: Bandyopadhyay, Anindita
  last_name: Bandyopadhyay
- first_name: Joshua
  full_name: Blakeslee, Joshua
  last_name: Blakeslee
- first_name: Ok
  full_name: Lee, Ok Ran
  last_name: Lee
- first_name: Jozef
  full_name: Mravec, Jozef
  last_name: Mravec
- first_name: Michael
  full_name: Sauer, Michael
  last_name: Sauer
- first_name: Boosaree
  full_name: Titapiwatanakun, Boosaree
  last_name: Titapiwatanakun
- first_name: Srinivas
  full_name: Makam, Srinivas N
  last_name: Makam
- first_name: Rodolphe
  full_name: Bouchard, Rodolphe
  last_name: Bouchard
- first_name: Markus
  full_name: Geisler, Markus
  last_name: Geisler
- first_name: Enrico
  full_name: Martinoia, Enrico
  last_name: Martinoia
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Wendy
  full_name: Peer, Wendy A
  last_name: Peer
- first_name: Angus
  full_name: Murphy, Angus S
  last_name: Murphy
citation:
  ama: 'Bandyopadhyay A, Blakeslee J, Lee O, et al. Interactions of PIN and PGP auxin
    transport mechanisms. In: Vol 35. Portland Press; 2007:137-141. doi:<a href="https://doi.org/10.1042/BST0350137">10.1042/BST0350137</a>'
  apa: Bandyopadhyay, A., Blakeslee, J., Lee, O., Mravec, J., Sauer, M., Titapiwatanakun,
    B., … Murphy, A. (2007). Interactions of PIN and PGP auxin transport mechanisms
    (Vol. 35, pp. 137–141). Presented at the Intercellular Signalling in Plants, Portland
    Press. <a href="https://doi.org/10.1042/BST0350137">https://doi.org/10.1042/BST0350137</a>
  chicago: Bandyopadhyay, Anindita, Joshua Blakeslee, Ok Lee, Jozef Mravec, Michael
    Sauer, Boosaree Titapiwatanakun, Srinivas Makam, et al. “Interactions of PIN and
    PGP Auxin Transport Mechanisms,” 35:137–41. Portland Press, 2007. <a href="https://doi.org/10.1042/BST0350137">https://doi.org/10.1042/BST0350137</a>.
  ieee: A. Bandyopadhyay <i>et al.</i>, “Interactions of PIN and PGP auxin transport
    mechanisms,” presented at the Intercellular Signalling in Plants, 2007, vol. 35,
    no. 1, pp. 137–141.
  ista: Bandyopadhyay A, Blakeslee J, Lee O, Mravec J, Sauer M, Titapiwatanakun B,
    Makam S, Bouchard R, Geisler M, Martinoia E, Friml J, Peer W, Murphy A. 2007.
    Interactions of PIN and PGP auxin transport mechanisms. Intercellular Signalling
    in Plants, Biochemical Society Transactions, vol. 35, 137–141.
  mla: Bandyopadhyay, Anindita, et al. <i>Interactions of PIN and PGP Auxin Transport
    Mechanisms</i>. Vol. 35, no. 1, Portland Press, 2007, pp. 137–41, doi:<a href="https://doi.org/10.1042/BST0350137">10.1042/BST0350137</a>.
  short: A. Bandyopadhyay, J. Blakeslee, O. Lee, J. Mravec, M. Sauer, B. Titapiwatanakun,
    S. Makam, R. Bouchard, M. Geisler, E. Martinoia, J. Friml, W. Peer, A. Murphy,
    in:, Portland Press, 2007, pp. 137–141.
conference:
  name: Intercellular Signalling in Plants
date_created: 2018-12-11T12:00:54Z
date_published: 2007-02-01T00:00:00Z
date_updated: 2021-01-12T07:40:30Z
day: '01'
doi: 10.1042/BST0350137
extern: 1
intvolume: '        35'
issue: '1'
month: '02'
page: 137 - 141
publication_status: published
publisher: Portland Press
publist_id: '3681'
quality_controlled: 0
status: public
title: Interactions of PIN and PGP auxin transport mechanisms
type: conference
volume: 35
year: '2007'
...