---
_id: '3050'
abstract:
- lang: eng
text: 'Plant development is governed by signaling molecules called phytohormones.
Typically, in certain developmental processes more than 1 hormone is implicated
and, thus, coordination of their overlapping activities is crucial for correct
plant development. However, molecular mechanisms underlying the hormonal crosstalk
are only poorly understood. Multiple hormones including cytokinin and auxin have
been implicated in the regulation of root development. Here we dissect the roles
of cytokinin in modulating growth of the primary root. We show that cytokinin
effect on root elongation occurs through ethylene signaling whereas cytokinin
effect on the root meristem size involves ethylene-independent modulation of transport-dependent
asymmetric auxin distribution. Exogenous or endogenous modification of cytokinin
levels and cytokinin signaling lead to specific changes in transcription of several
auxin efflux carrier genes from the PIN family having a direct impact on auxin
efflux from cultured cells and on auxin distribution in the root apex. We propose
a novel model for cytokinin action in regulating root growth: Cytokinin influences
cell-to-cell auxin transport by modification of expression of several auxin transport
components and thus modulates auxin distribution important for regulation of activity
and size of the root meristem.'
author:
- first_name: Kamil
full_name: Růžička, Kamil
last_name: Růžička
- first_name: Mária
full_name: Šimášková, Mária
last_name: Šimášková
- first_name: Jérôme
full_name: Duclercq, Jérôme
last_name: Duclercq
- first_name: Jan
full_name: Petrášek, Jan
last_name: Petrášek
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
- first_name: Sibu
full_name: Sibu Simon
id: 4542EF9A-F248-11E8-B48F-1D18A9856A87
last_name: Simon
orcid: 0000-0002-1998-6741
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Marc
full_name: Van Montagu, Marc C
last_name: Van Montagu
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
citation:
ama: Růžička K, Šimášková M, Duclercq J, et al. Cytokinin regulates root meristem
activity via modulation of the polar auxin transport. PNAS. 2009;106(11):4284-4289.
doi:10.1073/pnas.0900060106
apa: Růžička, K., Šimášková, M., Duclercq, J., Petrášek, J., Zažímalová, E., Simon,
S., … Benková, E. (2009). Cytokinin regulates root meristem activity via modulation
of the polar auxin transport. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.0900060106
chicago: Růžička, Kamil, Mária Šimášková, Jérôme Duclercq, Jan Petrášek, Eva Zažímalová,
Sibu Simon, Jiří Friml, Marc Van Montagu, and Eva Benková. “Cytokinin Regulates
Root Meristem Activity via Modulation of the Polar Auxin Transport.” PNAS.
National Academy of Sciences, 2009. https://doi.org/10.1073/pnas.0900060106.
ieee: K. Růžička et al., “Cytokinin regulates root meristem activity via
modulation of the polar auxin transport,” PNAS, vol. 106, no. 11. National
Academy of Sciences, pp. 4284–4289, 2009.
ista: Růžička K, Šimášková M, Duclercq J, Petrášek J, Zažímalová E, Simon S, Friml
J, Van Montagu M, Benková E. 2009. Cytokinin regulates root meristem activity
via modulation of the polar auxin transport. PNAS. 106(11), 4284–4289.
mla: Růžička, Kamil, et al. “Cytokinin Regulates Root Meristem Activity via Modulation
of the Polar Auxin Transport.” PNAS, vol. 106, no. 11, National Academy
of Sciences, 2009, pp. 4284–89, doi:10.1073/pnas.0900060106.
short: K. Růžička, M. Šimášková, J. Duclercq, J. Petrášek, E. Zažímalová, S. Simon,
J. Friml, M. Van Montagu, E. Benková, PNAS 106 (2009) 4284–4289.
date_created: 2018-12-11T12:01:04Z
date_published: 2009-03-17T00:00:00Z
date_updated: 2021-01-12T07:40:42Z
day: '17'
doi: 10.1073/pnas.0900060106
extern: 1
intvolume: ' 106'
issue: '11'
month: '03'
page: 4284 - 4289
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3652'
quality_controlled: 0
status: public
title: Cytokinin regulates root meristem activity via modulation of the polar auxin
transport
type: journal_article
volume: 106
year: '2009'
...