---
_id: '3092'
abstract:
- lang: eng
  text: The phytohormone auxin is vital to plant growth and development. A unique
    property of auxin among all other plant hormones is its cell-to-cell polar transport
    that requires activity of polarly localized PIN-FORMED (PIN) auxin efflux transporters.
    Despite the substantial molecular insight into the cellular PIN polarization,
    the mechanistic understanding for developmentally and environmentally regulated
    PIN polarization is scarce. The long-standing belief that auxin modulates its
    own transport by means of a positive feedback mechanism has inspired both experimentalists
    and theoreticians for more than two decades. Recently, theoretical models for
    auxin-dependent patterning in plants include the feedback between auxin transport
    and the PIN protein localization. These computer models aid to assess the complexity
    of plant development by testing and predicting plausible scenarios for various
    developmental processes that occur in planta. Although the majority of these models
    rely on purely heuristic principles, the most recent mechanistic models tentatively
    integrate biologically testable components into known cellular processes that
    underlie the PIN polarity regulation. The existing and emerging computational
    approaches to describe PIN polarization are presented and discussed in the light
    of recent experimental data on the PIN polar targeting.
author:
- first_name: Krzysztof T
  full_name: Wabnik, Krzysztof T
  id: 4DE369A4-F248-11E8-B48F-1D18A9856A87
  last_name: Wabnik
  orcid: 0000-0001-7263-0560
- first_name: Willy
  full_name: Govaerts, Willy
  last_name: Govaerts
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Jürgen
  full_name: Kleine Vehn, Jürgen
  last_name: Kleine Vehn
citation:
  ama: 'Wabnik KT, Govaerts W, Friml J, Kleine Vehn J. Feedback models for polarized
    auxin transport: An emerging trend. <i>Molecular BioSystems</i>. 2011;7(8):2352-2359.
    doi:<a href="https://doi.org/10.1039/c1mb05109a">10.1039/c1mb05109a</a>'
  apa: 'Wabnik, K. T., Govaerts, W., Friml, J., &#38; Kleine Vehn, J. (2011). Feedback
    models for polarized auxin transport: An emerging trend. <i>Molecular BioSystems</i>.
    Royal Society of Chemistry. <a href="https://doi.org/10.1039/c1mb05109a">https://doi.org/10.1039/c1mb05109a</a>'
  chicago: 'Wabnik, Krzysztof T, Willy Govaerts, Jiří Friml, and Jürgen Kleine Vehn.
    “Feedback Models for Polarized Auxin Transport: An Emerging Trend.” <i>Molecular
    BioSystems</i>. Royal Society of Chemistry, 2011. <a href="https://doi.org/10.1039/c1mb05109a">https://doi.org/10.1039/c1mb05109a</a>.'
  ieee: 'K. T. Wabnik, W. Govaerts, J. Friml, and J. Kleine Vehn, “Feedback models
    for polarized auxin transport: An emerging trend,” <i>Molecular BioSystems</i>,
    vol. 7, no. 8. Royal Society of Chemistry, pp. 2352–2359, 2011.'
  ista: 'Wabnik KT, Govaerts W, Friml J, Kleine Vehn J. 2011. Feedback models for
    polarized auxin transport: An emerging trend. Molecular BioSystems. 7(8), 2352–2359.'
  mla: 'Wabnik, Krzysztof T., et al. “Feedback Models for Polarized Auxin Transport:
    An Emerging Trend.” <i>Molecular BioSystems</i>, vol. 7, no. 8, Royal Society
    of Chemistry, 2011, pp. 2352–59, doi:<a href="https://doi.org/10.1039/c1mb05109a">10.1039/c1mb05109a</a>.'
  short: K.T. Wabnik, W. Govaerts, J. Friml, J. Kleine Vehn, Molecular BioSystems
    7 (2011) 2352–2359.
date_created: 2018-12-11T12:01:20Z
date_published: 2011-06-10T00:00:00Z
date_updated: 2021-01-12T07:41:00Z
day: '10'
doi: 10.1039/c1mb05109a
extern: '1'
external_id:
  pmid:
  - '21660355'
intvolume: '         7'
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/21660355
month: '06'
oa: 1
oa_version: Published Version
page: 2352 - 2359
pmid: 1
publication: Molecular BioSystems
publication_status: published
publisher: Royal Society of Chemistry
publist_id: '3608'
quality_controlled: '1'
status: public
title: 'Feedback models for polarized auxin transport: An emerging trend'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2011'
...