---
_id: '3102'
abstract:
- lang: eng
text: 'Multicellular organisms depend on cell production, cell fate specification,
and correct patterning to shape their adult body. In plants, auxin plays a prominent
role in the timely coordination of these different cellular processes. A well-studied
example is lateral root initiation, in which auxin triggers founder cell specification
and cell cycle activation of xylem pole–positioned pericycle cells. Here, we report
that the E2Fa transcription factor of Arabidopsis thaliana is an essential component
that regulates the asymmetric cell division marking lateral root initiation. Moreover,
we demonstrate that E2Fa expression is regulated by the LATERAL ORGAN BOUNDARY
DOMAIN18/LATERAL ORGAN BOUNDARY DOMAIN33 (LBD18/LBD33) dimer that is, in turn,
regulated by the auxin signaling pathway. LBD18/LBD33 mediates lateral root organogenesis
through E2Fa transcriptional activation, whereas E2Fa expression under control
of the LBD18 promoter eliminates the need for LBD18. Besides lateral root initiation,
vascular patterning is disrupted in E2Fa knockout plants, similarly as it is affected
in auxin signaling and lbd mutants, indicating that the transcriptional induction
of E2Fa through LBDs represents a general mechanism for auxin-dependent cell cycle
activation. Our data illustrate how a conserved mechanism driving cell cycle entry
has been adapted evolutionarily to connect auxin signaling with control of processes
determining plant architecture. '
author:
- first_name: Barbara
full_name: Berckmans, Barbara
last_name: Berckmans
- first_name: Valya
full_name: Vassileva, Valya
last_name: Vassileva
- first_name: Stephan
full_name: Schmid, Stephan P
last_name: Schmid
- first_name: Sara
full_name: Maes, Sara
last_name: Maes
- first_name: Boris
full_name: Parizot, Boris
last_name: Parizot
- first_name: Satoshi
full_name: Naramoto, Satoshi
last_name: Naramoto
- first_name: Zoltan
full_name: Magyar, Zoltan
last_name: Magyar
- first_name: Claire
full_name: Lessa Alvim Kamei, Claire
last_name: Lessa Alvim Kamei
- first_name: Csaba
full_name: Koncz, Csaba
last_name: Koncz
- first_name: Laszlo
full_name: Bögre, Laszlo
last_name: Bögre
- first_name: Geert
full_name: Persiau, Geert
last_name: Persiau
- first_name: Geert
full_name: De Jaeger, Geert
last_name: De Jaeger
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Rüdiger
full_name: Simon, Rüdiger
last_name: Simon
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Lieven
full_name: de Veyldera, Lieven
last_name: De Veyldera
citation:
ama: Berckmans B, Vassileva V, Schmid S, et al. Auxin Dependent cell cycle reactivation
through transcriptional regulation of arabidopsis E2Fa by lateral organ boundary
proteins. Plant Cell. 2011;23(10):3671-3683. doi:10.1105/tpc.111.088377
apa: Berckmans, B., Vassileva, V., Schmid, S., Maes, S., Parizot, B., Naramoto,
S., … De Veyldera, L. (2011). Auxin Dependent cell cycle reactivation through
transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins.
Plant Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.111.088377
chicago: Berckmans, Barbara, Valya Vassileva, Stephan Schmid, Sara Maes, Boris Parizot,
Satoshi Naramoto, Zoltan Magyar, et al. “Auxin Dependent Cell Cycle Reactivation
through Transcriptional Regulation of Arabidopsis E2Fa by Lateral Organ Boundary
Proteins.” Plant Cell. American Society of Plant Biologists, 2011. https://doi.org/10.1105/tpc.111.088377.
ieee: B. Berckmans et al., “Auxin Dependent cell cycle reactivation through
transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins,”
Plant Cell, vol. 23, no. 10. American Society of Plant Biologists, pp.
3671–3683, 2011.
ista: Berckmans B, Vassileva V, Schmid S, Maes S, Parizot B, Naramoto S, Magyar
Z, Lessa Alvim Kamei C, Koncz C, Bögre L, Persiau G, De Jaeger G, Friml J, Simon
R, Beeckman T, De Veyldera L. 2011. Auxin Dependent cell cycle reactivation through
transcriptional regulation of arabidopsis E2Fa by lateral organ boundary proteins.
Plant Cell. 23(10), 3671–3683.
mla: Berckmans, Barbara, et al. “Auxin Dependent Cell Cycle Reactivation through
Transcriptional Regulation of Arabidopsis E2Fa by Lateral Organ Boundary Proteins.”
Plant Cell, vol. 23, no. 10, American Society of Plant Biologists, 2011,
pp. 3671–83, doi:10.1105/tpc.111.088377.
short: B. Berckmans, V. Vassileva, S. Schmid, S. Maes, B. Parizot, S. Naramoto,
Z. Magyar, C. Lessa Alvim Kamei, C. Koncz, L. Bögre, G. Persiau, G. De Jaeger,
J. Friml, R. Simon, T. Beeckman, L. De Veyldera, Plant Cell 23 (2011) 3671–3683.
date_created: 2018-12-11T12:01:24Z
date_published: 2011-10-14T00:00:00Z
date_updated: 2021-01-12T07:41:04Z
day: '14'
doi: 10.1105/tpc.111.088377
extern: 1
intvolume: ' 23'
issue: '10'
month: '10'
page: 3671 - 3683
publication: Plant Cell
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3598'
quality_controlled: 0
status: public
title: Auxin Dependent cell cycle reactivation through transcriptional regulation
of arabidopsis E2Fa by lateral organ boundary proteins
type: journal_article
volume: 23
year: '2011'
...