---
_id: '3454'
abstract:
- lang: eng
  text: The study of gene expression and regulation in the central nervous system
    (CNS) is a daunting task because of the diversity of neuronal phenotypes and the
    complexity of many protein classes. Molecular cloning revealed the presence of
    a large number of different protein families in the CNS, each comprising several
    members. Ligand-gated ion channels may serve as an example to illustrate this
    point (for review, see Unwin, 1993). Heterologous expression combined with electrophysiological
    analysis suggests that ligand-gated channels are multimeric proteins with functional
    properties depending on the subunit composition. Very little is known, however,
    about how the functional properties of the recombinant and native receptors relate
    to each other. Thus, it is of eminent importance to elucidate the subunit expression
    profile in different types of neurons in the CNS and to correlate this with the
    functional properties of the native receptors.
article_processing_charge: No
author:
- first_name: Hannah
  full_name: Monyer, Hannah
  last_name: Monyer
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: 'Monyer H, Jonas PM. Polymerase chain reaction analysis of ion channel expression
    in single neurons of brain slices. In: Sakmann B, Neher E, eds. <i>Single-Channel
    Recording</i>. Plenum; 1995:357-373. doi:<a href="https://doi.org/10.1007/978-1-4419-1229-9_16">10.1007/978-1-4419-1229-9_16</a>'
  apa: Monyer, H., &#38; Jonas, P. M. (1995). Polymerase chain reaction analysis of
    ion channel expression in single neurons of brain slices. In B. Sakmann &#38;
    E. Neher (Eds.), <i>Single-channel recording</i> (pp. 357–373). Plenum. <a href="https://doi.org/10.1007/978-1-4419-1229-9_16">https://doi.org/10.1007/978-1-4419-1229-9_16</a>
  chicago: Monyer, Hannah, and Peter M Jonas. “Polymerase Chain Reaction Analysis
    of Ion Channel Expression in Single Neurons of Brain Slices.” In <i>Single-Channel
    Recording</i>, edited by Bert Sakmann and Erwin Neher, 357–73. Plenum, 1995. <a
    href="https://doi.org/10.1007/978-1-4419-1229-9_16">https://doi.org/10.1007/978-1-4419-1229-9_16</a>.
  ieee: H. Monyer and P. M. Jonas, “Polymerase chain reaction analysis of ion channel
    expression in single neurons of brain slices,” in <i>Single-channel recording</i>,
    B. Sakmann and E. Neher, Eds. Plenum, 1995, pp. 357–373.
  ista: 'Monyer H, Jonas PM. 1995.Polymerase chain reaction analysis of ion channel
    expression in single neurons of brain slices. In: Single-channel recording. ,
    357–373.'
  mla: Monyer, Hannah, and Peter M. Jonas. “Polymerase Chain Reaction Analysis of
    Ion Channel Expression in Single Neurons of Brain Slices.” <i>Single-Channel Recording</i>,
    edited by Bert Sakmann and Erwin Neher, Plenum, 1995, pp. 357–73, doi:<a href="https://doi.org/10.1007/978-1-4419-1229-9_16">10.1007/978-1-4419-1229-9_16</a>.
  short: H. Monyer, P.M. Jonas, in:, B. Sakmann, E. Neher (Eds.), Single-Channel Recording,
    Plenum, 1995, pp. 357–373.
date_created: 2018-12-11T12:03:25Z
date_published: 1995-01-01T00:00:00Z
date_updated: 2022-06-28T09:13:01Z
day: '01'
doi: 10.1007/978-1-4419-1229-9_16
editor:
- first_name: Bert
  full_name: Sakmann, Bert
  last_name: Sakmann
- first_name: Erwin
  full_name: Neher, Erwin
  last_name: Neher
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/chapter/10.1007/978-1-4419-1229-9_16
month: '01'
oa_version: None
page: 357 - 373
publication: Single-channel recording
publication_identifier:
  isbn:
  - 978-0-306-44870-6
publication_status: published
publisher: Plenum
publist_id: '2933'
quality_controlled: '1'
status: public
title: Polymerase chain reaction analysis of ion channel expression in single neurons
  of brain slices
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '1995'
...
