{"page":"419 - 424","acknowledgement":"See comment by Nicoll RA, Malenka RC (1998) Science 281:360-361\r\n","publist_id":"2900","doi":"10.1126/science.281.5375.419","issue":"5375","_id":"3487","publication":"Science","date_updated":"2022-08-29T14:52:38Z","language":[{"iso":"eng"}],"day":"17","publisher":"American Association for the Advancement of Science","volume":281,"year":"1998","external_id":{"pmid":["9665886 "]},"publication_status":"published","citation":{"ama":"Jonas PM, Bischofberger J, Sandkühler J. Corelease of two fast neurotransmitters at a central synapse. <i>Science</i>. 1998;281(5375):419-424. doi:<a href=\"https://doi.org/10.1126/science.281.5375.419\">10.1126/science.281.5375.419</a>","short":"P.M. Jonas, J. Bischofberger, J. Sandkühler, Science 281 (1998) 419–424.","ista":"Jonas PM, Bischofberger J, Sandkühler J. 1998. Corelease of two fast neurotransmitters at a central synapse. Science. 281(5375), 419–424.","apa":"Jonas, P. M., Bischofberger, J., &#38; Sandkühler, J. (1998). Corelease of two fast neurotransmitters at a central synapse. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.281.5375.419\">https://doi.org/10.1126/science.281.5375.419</a>","mla":"Jonas, Peter M., et al. “Corelease of Two Fast Neurotransmitters at a Central Synapse.” <i>Science</i>, vol. 281, no. 5375, American Association for the Advancement of Science, 1998, pp. 419–24, doi:<a href=\"https://doi.org/10.1126/science.281.5375.419\">10.1126/science.281.5375.419</a>.","ieee":"P. M. Jonas, J. Bischofberger, and J. Sandkühler, “Corelease of two fast neurotransmitters at a central synapse,” <i>Science</i>, vol. 281, no. 5375. American Association for the Advancement of Science, pp. 419–424, 1998.","chicago":"Jonas, Peter M, Joseph Bischofberger, and Jürgen Sandkühler. “Corelease of Two Fast Neurotransmitters at a Central Synapse.” <i>Science</i>. American Association for the Advancement of Science, 1998. <a href=\"https://doi.org/10.1126/science.281.5375.419\">https://doi.org/10.1126/science.281.5375.419</a>."},"intvolume":"       281","author":[{"full_name":"Jonas, Peter M","last_name":"Jonas","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5001-4804"},{"first_name":"Joseph","last_name":"Bischofberger","full_name":"Bischofberger, Joseph"},{"first_name":"Jürgen","last_name":"Sandkühler","full_name":"Sandkühler, Jürgen"}],"abstract":[{"lang":"eng","text":"It is widely accepted that individual neurons in the central nervous system release only a single fast transmitter. The possibility of corelease of fast neurotransmitters was examined by making paired recordings from synaptically connected neurons in spinal cord slices. Unitary inhibitory postsynaptic currents generated at interneuron-motoneuron synapses consisted of a strychnine-sensitive, glycine receptor-mediated component and a bicuculline-sensitive, γ-aminobutyric acid (GABA)(A) receptor-mediated component. These results indicate that spinal interneurons release both glycine and GABA to activate functionally distinct receptors in their postsynaptic target cells. A subset of miniature synaptic currents also showed both components, consistent with corelease from individual synaptic vesicles."}],"scopus_import":"1","pmid":1,"quality_controlled":"1","article_type":"original","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","date_published":"1998-07-17T00:00:00Z","oa_version":"None","date_created":"2018-12-11T12:03:35Z","month":"07","publication_identifier":{"issn":["0036-8075"]},"type":"journal_article","extern":"1","title":"Corelease of two fast neurotransmitters at a central synapse","status":"public"}