--- res: bibo_abstract: - In the cerebral cortex, GABAergic interneurons are often regarded as fast-spiking cells. We have identified a type of slow-spiking interneuron that offers distinct contributions to network activity. “Ivy” cells, named after their dense and fine axons innervating mostly basal and oblique pyramidal cell dendrites, are more numerous than the parvalbumin-expressing basket, bistratified, or axo-axonic cells. Ivy cells express nitric oxide synthase, neuropeptide Y, and high levels of GABA(A) receptor alpha 1 subunit; they discharge at a low frequency with wide spikes in vivo, yet are distinctively phase-locked to behaviorally relevant network rhythms including theta, gamma, and ripple oscillations. Paired recordings in vitro showed that Ivy cells receive depressing EPSPs from pyramidal cells, which in turn receive slowly rising and decaying inhibitory input from Ivy cells. In contrast to fast-spiking interneurons operating with millisecond precision, the highly abundant Ivy cells express presynaptically acting neuromodulators and regulate the excitability of pyramidal cell dendrites through slowly rising and decaying GABAergic inputs.@eng bibo_authorlist: - foaf_Person: foaf_givenName: Pablo foaf_name: Fuentealba,Pablo foaf_surname: Fuentealba - foaf_Person: foaf_givenName: Rahima foaf_name: Begum,Rahima foaf_surname: Begum - foaf_Person: foaf_givenName: Marco foaf_name: Capogna,Marco foaf_surname: Capogna - foaf_Person: foaf_givenName: Shozo foaf_name: Jinno,Shozo foaf_surname: Jinno - foaf_Person: foaf_givenName: Laszlo foaf_name: Marton,Laszlo F foaf_surname: Marton - foaf_Person: foaf_givenName: Jozsef L foaf_name: Jozsef Csicsvari foaf_surname: Csicsvari foaf_workInfoHomepage: http://www.librecat.org/personId=3FA14672-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0002-5193-4036 - foaf_Person: foaf_givenName: Alex foaf_name: Thomson,Alex foaf_surname: Thomson - foaf_Person: foaf_givenName: Péter foaf_name: Somogyi, Péter foaf_surname: Somogyi - foaf_Person: foaf_givenName: Thomas foaf_name: Klausberger,Thomas foaf_surname: Klausberger bibo_doi: 10.1016/j.neuron.2008.01.034 bibo_issue: '6' bibo_volume: 57 dct_date: 2008^xs_gYear dct_publisher: Elsevier@ dct_title: 'Ivy cells: A population of nitric-oxide-producing, slow-spiking GABAergic neurons and their involvement in hippocampal network activity@' ...