---
res:
  bibo_abstract:
  - In spatially heterogeneous environments, natural selection for maintenance of
    adaptation to habitats that contribute little to the population's reproduction
    is weak. In this paper we model a mechanism that can result in loss of fitness
    in such marginal habitats, and thus lead to specialisation on the main habitat.
    It involves accumulation of mutations that are deleterious in the marginal habitat
    but neutral or nearly so in the main habitat (mutations deleterious in the main
    habitat and neutral in the marginal habitat have a negligible influence). If the
    contribution of the marginal habitat to total reproduction in the absence of the
    mutations is less than a threshold value, selection is too weak to counter accumulation
    of such mutations. A positive feedback then results in loss of fitness in the
    marginal habitat. This mechanism does not require antagonistic pleiotropy in adaptation
    to different habitats, although antagonistic pleiotropy facilitates the mutational
    collapse of fitness in the marginal habitat. We suggest that deleterious mutations
    with habitat-specific expression may play a role in the evolution of ecological
    specialisation and promote evolutionary conservatism of ecological niches.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Tadeusz
      foaf_name: Kawecki, Tadeusz
      foaf_surname: Kawecki
  - foaf_Person:
      foaf_givenName: Nicholas H
      foaf_name: Barton, Nicholas H
      foaf_surname: Barton
      foaf_workInfoHomepage: http://www.librecat.org/personId=4880FE40-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8548-5240
  - foaf_Person:
      foaf_givenName: James
      foaf_name: Fry, James
      foaf_surname: Fry
  bibo_doi: 10.1046/j.1420-9101.1997.10030407.x
  bibo_issue: '3'
  bibo_volume: 10
  dct_date: 1997^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1010-061X
  dct_language: eng
  dct_publisher: Wiley-Blackwell@
  dct_title: Mutational collapse of fitness in marginal habitats and the evolution
    of ecological specialisation@
...