{"external_id":{"pmid":["28568824"]},"date_published":"1991-05-01T00:00:00Z","pmid":1,"abstract":[{"lang":"eng","text":"We investigate the probability of fixation of a chromosome rearrangement in a subdivided population, concentrating on the limit where migration is so large relative to selection (m ≫ s) that the population can be thought of as being continuously distributed. We study two demes, and one- and two-dimensional populations. For two demes, the probability of fixation in the limit of high migration approximates that of a population with twice the size of a single deme: migration therefore greatly reduces the fixation probability. However, this behavior does not extend to a large array of demes. Then, the fixation probability depends primarily on neighborhood size (Nb), and may be appreciable even with strong selection and free gene flow (≈exp(-B·Nb) in one dimension, ≈exp(-B\\cdotNb) in two dimensions). Our results are close to those for the more tractable case of a polygenic character under disruptive selection."}],"article_type":"original","publist_id":"2735","author":[{"full_name":"Barton, Nicholas H","first_name":"Nicholas H","last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8548-5240"},{"first_name":"Shahin","full_name":"Rouhani, Shahin","last_name":"Rouhani"}],"language":[{"iso":"eng"}],"issue":"3","publication_status":"published","_id":"3648","article_processing_charge":"No","publication_identifier":{"issn":["0014-3820"],"eissn":["1558-5646"]},"date_updated":"2022-03-02T10:37:19Z","extern":"1","date_created":"2018-12-11T12:04:25Z","main_file_link":[{"url":"http://www.jstor.org/stable/2409908"}],"volume":45,"page":"499 - 517","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","publication":"Evolution","month":"05","quality_controlled":"1","intvolume":"        45","oa_version":"None","title":"The probability of fixation of a new karyotype in a continuous population","day":"01","status":"public","doi":"10.1111/j.1558-5646.1991.tb04326.x","publisher":"Wiley-Blackwell","citation":{"ieee":"N. H. Barton and S. Rouhani, “The probability of fixation of a new karyotype in a continuous population,” <i>Evolution</i>, vol. 45, no. 3. Wiley-Blackwell, pp. 499–517, 1991.","chicago":"Barton, Nicholas H, and Shahin Rouhani. “The Probability of Fixation of a New Karyotype in a Continuous Population.” <i>Evolution</i>. Wiley-Blackwell, 1991. <a href=\"https://doi.org/10.1111/j.1558-5646.1991.tb04326.x\">https://doi.org/10.1111/j.1558-5646.1991.tb04326.x</a>.","short":"N.H. Barton, S. Rouhani, Evolution 45 (1991) 499–517.","apa":"Barton, N. H., &#38; Rouhani, S. (1991). The probability of fixation of a new karyotype in a continuous population. <i>Evolution</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.1558-5646.1991.tb04326.x\">https://doi.org/10.1111/j.1558-5646.1991.tb04326.x</a>","ista":"Barton NH, Rouhani S. 1991. The probability of fixation of a new karyotype in a continuous population. Evolution. 45(3), 499–517.","mla":"Barton, Nicholas H., and Shahin Rouhani. “The Probability of Fixation of a New Karyotype in a Continuous Population.” <i>Evolution</i>, vol. 45, no. 3, Wiley-Blackwell, 1991, pp. 499–517, doi:<a href=\"https://doi.org/10.1111/j.1558-5646.1991.tb04326.x\">10.1111/j.1558-5646.1991.tb04326.x</a>.","ama":"Barton NH, Rouhani S. The probability of fixation of a new karyotype in a continuous population. <i>Evolution</i>. 1991;45(3):499-517. doi:<a href=\"https://doi.org/10.1111/j.1558-5646.1991.tb04326.x\">10.1111/j.1558-5646.1991.tb04326.x</a>"},"type":"journal_article","year":"1991"}