---
_id: '3665'
abstract:
- lang: eng
  text: The rate of gene flow across a hybrid zone may be reduced by the presence
    of a physical barrier, by a reduction of population density caused by reduced
    fitness of hybrids (the “hybrid sink” effect), and by linkage. If the reduction
    in hybrid fitness is not extreme, the strength of the barrier to gene flow caused
    by these effects is. Here, w is the width of the cline; ρ* is the carrying capacity;
    W̄* is the mean fitness of the population, excluding effects of density; R is
    the strength of density-dependent regulation; and r̄ is the harmonic mean recombination
    rate between the locus whose flow is being calculated, and loci under selection.
    +, 0 denote populations outside the hybrid zone, and at its centre, respectively.
    This relation is illustrated using data from hybrid ones in Bombina and Podisma,
    and its implications for interpretation of data from nature are discussed.
acknowledgement: I would like to thank Shahin Rouhani and Richard Nichols for their
  helpful comments on the manuscript, and the latter for providing the data used in
  fig. 3. This work was supported by a grant from the Science and Engineering Research
  Council (GR/C/91529).
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Barton NH. The effects of linkage and density-dependent regulation on gene
    flow. <i>Heredity</i>. 1986;57:415-426.
  apa: Barton, N. H. (1986). The effects of linkage and density-dependent regulation
    on gene flow. <i>Heredity</i>. Nature Publishing Group.
  chicago: Barton, Nicholas H. “The Effects of Linkage and Density-Dependent Regulation
    on Gene Flow.” <i>Heredity</i>. Nature Publishing Group, 1986.
  ieee: N. H. Barton, “The effects of linkage and density-dependent regulation on
    gene flow,” <i>Heredity</i>, vol. 57. Nature Publishing Group, pp. 415–426, 1986.
  ista: Barton NH. 1986. The effects of linkage and density-dependent regulation on
    gene flow. Heredity. 57, 415–426.
  mla: Barton, Nicholas H. “The Effects of Linkage and Density-Dependent Regulation
    on Gene Flow.” <i>Heredity</i>, vol. 57, Nature Publishing Group, 1986, pp. 415–26.
  short: N.H. Barton, Heredity 57 (1986) 415–426.
date_created: 2018-12-11T12:04:30Z
date_published: 1986-01-01T00:00:00Z
date_updated: 2022-02-01T14:31:29Z
day: '01'
extern: '1'
intvolume: '        57'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.nature.com/articles/hdy1986142
month: '01'
oa: 1
oa_version: Published Version
page: 415 - 426
publication: Heredity
publication_identifier:
  eissn:
  - 1365-2540
  issn:
  - 0018-067X
publication_status: published
publisher: Nature Publishing Group
publist_id: '2718'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The effects of linkage and density-dependent regulation on gene flow
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 57
year: '1986'
...