---
_id: '3673'
abstract:
- lang: eng
  text: The effect of a cline as a barrier to gene flow at closely linked, weakly
    selected loci is investigated using a continuous diffusion model. It is shown
    that a linked cline induces a step in the frequency of a neutral allele, which
    is proportional to the gradient in neutral allele frequency and to the inverse
    of the recombination rate. A barrier to dispersal or a local region of low abundance
    has a similar effect (Nagylaki, 1976). The cline will block the flow of neutral
    alleles over a region of chromosome roughly 2s/t map units long. However, a slightly
    advantageous allele will be little affected, and must be very tightly linked to
    be delayed for long.
acknowledgement: "I would like to thank Dr G. M. Hewitt for stimulating discussions,
  and for his comments on the manuscript. This work was supported by the Natural Environmental
  Research Council.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Barton NH. Gene flow past a cline. <i>Heredity</i>. 1979;43(3):333-339. doi:<a
    href="https://doi.org/10.1038/hdy.1979.86">10.1038/hdy.1979.86</a>
  apa: Barton, N. H. (1979). Gene flow past a cline. <i>Heredity</i>. Springer Nature.
    <a href="https://doi.org/10.1038/hdy.1979.86">https://doi.org/10.1038/hdy.1979.86</a>
  chicago: Barton, Nicholas H. “Gene Flow Past a Cline.” <i>Heredity</i>. Springer
    Nature, 1979. <a href="https://doi.org/10.1038/hdy.1979.86">https://doi.org/10.1038/hdy.1979.86</a>.
  ieee: N. H. Barton, “Gene flow past a cline,” <i>Heredity</i>, vol. 43, no. 3. Springer
    Nature, pp. 333–339, 1979.
  ista: Barton NH. 1979. Gene flow past a cline. Heredity. 43(3), 333–339.
  mla: Barton, Nicholas H. “Gene Flow Past a Cline.” <i>Heredity</i>, vol. 43, no.
    3, Springer Nature, 1979, pp. 333–39, doi:<a href="https://doi.org/10.1038/hdy.1979.86">10.1038/hdy.1979.86</a>.
  short: N.H. Barton, Heredity 43 (1979) 333–339.
date_created: 2018-12-11T12:04:33Z
date_published: 1979-12-01T00:00:00Z
date_updated: 2021-12-15T15:16:50Z
day: '01'
doi: 10.1038/hdy.1979.86
extern: '1'
intvolume: '        43'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.nature.com/articles/hdy197986
month: '12'
oa: 1
oa_version: Published Version
page: 333 - 339
publication: Heredity
publication_identifier:
  eissn:
  - 1365-2540
  issn:
  - 0018-067X
publication_status: published
publisher: Springer Nature
publist_id: '2710'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gene flow past a cline
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 43
year: '1979'
...