---
res:
  bibo_abstract:
  - "Within systems biology there is an increasing interest in the stochastic behavior
    of biochemical reaction networks. An appropriate stochastic description is provided
    by the chemical master equation, which represents a continuous- time Markov chain
    (CTMC).\r\nStandard Uniformization (SU) is an efficient method for the transient
    analysis of CTMCs. For systems with very different time scales, such as biochemical
    reaction networks, SU is computationally expensive. In these cases, a variant
    of SU, called adaptive uniformization (AU), is known to reduce the large number
    of iterations needed by SU. The additional difficulty of AU is that it requires
    the solution of a birth process.\r\nIn this paper we present an on-the-fly variant
    of AU, where we improve the original algorithm for AU at the cost of a small approximation
    error. By means of several examples, we show that our approach is particularly
    well-suited for biochemical reaction networks.@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Frédéric
      foaf_name: Didier, Frédéric
      foaf_surname: Didier
  - foaf_Person:
      foaf_givenName: Thomas A
      foaf_name: Henzinger, Thomas A
      foaf_surname: Henzinger
      foaf_workInfoHomepage: http://www.librecat.org/personId=40876CD8-F248-11E8-B48F-1D18A9856A87
    orcid: 0000−0002−2985−7724
  - foaf_Person:
      foaf_givenName: Maria
      foaf_name: Mateescu, Maria
      foaf_surname: Mateescu
      foaf_workInfoHomepage: http://www.librecat.org/personId=3B43276C-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Verena
      foaf_name: Wolf, Verena
      foaf_surname: Wolf
  bibo_doi: 10.1109/HiBi.2009.23
  bibo_issue: '6'
  bibo_volume: 4
  dct_date: 2009^xs_gYear
  dct_identifier:
  - UT:000275038300017
  dct_language: eng
  dct_publisher: IEEE@
  dct_title: Fast adaptive uniformization of the chemical master equation@
...
