{"date_updated":"2021-01-12T07:53:38Z","day":"01","quality_controlled":0,"abstract":[{"lang":"eng","text":"We present an efficient algorithm for generating a small set of coarse alignments between interacting proteins using meaningful features on their surfaces. The proteins are treated as rigid bodies, but the results are more generally useful as the produced configurations can serve as input to local improvement algorithms that allow for protein flexibility. We apply our algorithm to a diverse set of protein complexes from the Protein Data Bank, demonstrating the effectivity of our algorithm, both for bound and for unbound protein docking problems."}],"title":"Coarse and reliable geometric alignment for protein docking","_id":"3982","date_created":"2018-12-11T12:06:16Z","page":"64 - 75","publication_status":"published","author":[{"full_name":"Wang, Yusu","last_name":"Wang","first_name":"Yusu"},{"full_name":"Agarwal, Pankaj K","first_name":"Pankaj","last_name":"Agarwal"},{"full_name":"Brown, Paul","first_name":"Paul","last_name":"Brown"},{"id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","full_name":"Herbert Edelsbrunner","first_name":"Herbert","last_name":"Edelsbrunner","orcid":"0000-0002-9823-6833"},{"first_name":"Johannes","last_name":"Rudolph","full_name":"Rudolph, Johannes"}],"citation":{"mla":"Wang, Yusu, et al. <i>Coarse and Reliable Geometric Alignment for Protein Docking</i>. World Scientific Publishing, 2005, pp. 64–75, doi:<a href=\"https://doi.org/10.1142/9789812702456_0007\">10.1142/9789812702456_0007</a>.","apa":"Wang, Y., Agarwal, P., Brown, P., Edelsbrunner, H., &#38; Rudolph, J. (2005). Coarse and reliable geometric alignment for protein docking (pp. 64–75). Presented at the PSB: Pacific Symposium on Biocomputing, World Scientific Publishing. <a href=\"https://doi.org/10.1142/9789812702456_0007\">https://doi.org/10.1142/9789812702456_0007</a>","ama":"Wang Y, Agarwal P, Brown P, Edelsbrunner H, Rudolph J. Coarse and reliable geometric alignment for protein docking. In: World Scientific Publishing; 2005:64-75. doi:<a href=\"https://doi.org/10.1142/9789812702456_0007\">10.1142/9789812702456_0007</a>","chicago":"Wang, Yusu, Pankaj Agarwal, Paul Brown, Herbert Edelsbrunner, and Johannes Rudolph. “Coarse and Reliable Geometric Alignment for Protein Docking,” 64–75. World Scientific Publishing, 2005. <a href=\"https://doi.org/10.1142/9789812702456_0007\">https://doi.org/10.1142/9789812702456_0007</a>.","short":"Y. Wang, P. Agarwal, P. Brown, H. Edelsbrunner, J. Rudolph, in:, World Scientific Publishing, 2005, pp. 64–75.","ieee":"Y. Wang, P. Agarwal, P. Brown, H. Edelsbrunner, and J. Rudolph, “Coarse and reliable geometric alignment for protein docking,” presented at the PSB: Pacific Symposium on Biocomputing, 2005, pp. 64–75.","ista":"Wang Y, Agarwal P, Brown P, Edelsbrunner H, Rudolph J. 2005. Coarse and reliable geometric alignment for protein docking. PSB: Pacific Symposium on Biocomputing, 64–75."},"month":"01","type":"conference","date_published":"2005-01-01T00:00:00Z","conference":{"name":"PSB: Pacific Symposium on Biocomputing"},"extern":1,"publisher":"World Scientific Publishing","doi":"10.1142/9789812702456_0007","publist_id":"2143","year":"2005","status":"public"}