{"article_processing_charge":"No","page":"83 - 102","doi":"10.1016/S0166-218X(98)00067-5","main_file_link":[{"url":"https://www.sciencedirect.com/science/article/pii/S0166218X98000675?via%3Dihub","open_access":"1"}],"publication_status":"published","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","month":"11","title":"On the definition and the construction of pockets in macromolecules","oa":1,"issue":"1-3","date_created":"2018-12-11T12:06:26Z","pmid":1,"_id":"4013","external_id":{"pmid":["9390238"]},"publication_identifier":{"issn":["0166-218X"]},"author":[{"orcid":"0000-0002-9823-6833","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","first_name":"Herbert","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner"},{"first_name":"Michael","full_name":"Facello, Michael","last_name":"Facello"},{"first_name":"Jie","last_name":"Liang","full_name":"Liang, Jie"}],"extern":"1","intvolume":"        88","acknowledgement":"The authors thank Ping Fu and Ernst Miicke for their contributions to the alpha shapes software in which the pockets software is embedded. ","quality_controlled":"1","status":"public","day":"09","publication":"Discrete Applied Mathematics","article_type":"original","date_updated":"2022-08-25T15:06:30Z","publisher":"Elsevier","scopus_import":"1","type":"journal_article","language":[{"iso":"eng"}],"citation":{"chicago":"Edelsbrunner, Herbert, Michael Facello, and Jie Liang. “On the Definition and the Construction of Pockets in Macromolecules.” <i>Discrete Applied Mathematics</i>. Elsevier, 1998. <a href=\"https://doi.org/10.1016/S0166-218X(98)00067-5\">https://doi.org/10.1016/S0166-218X(98)00067-5</a>.","apa":"Edelsbrunner, H., Facello, M., &#38; Liang, J. (1998). On the definition and the construction of pockets in macromolecules. <i>Discrete Applied Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/S0166-218X(98)00067-5\">https://doi.org/10.1016/S0166-218X(98)00067-5</a>","short":"H. Edelsbrunner, M. Facello, J. Liang, Discrete Applied Mathematics 88 (1998) 83–102.","mla":"Edelsbrunner, Herbert, et al. “On the Definition and the Construction of Pockets in Macromolecules.” <i>Discrete Applied Mathematics</i>, vol. 88, no. 1–3, Elsevier, 1998, pp. 83–102, doi:<a href=\"https://doi.org/10.1016/S0166-218X(98)00067-5\">10.1016/S0166-218X(98)00067-5</a>.","ama":"Edelsbrunner H, Facello M, Liang J. On the definition and the construction of pockets in macromolecules. <i>Discrete Applied Mathematics</i>. 1998;88(1-3):83-102. doi:<a href=\"https://doi.org/10.1016/S0166-218X(98)00067-5\">10.1016/S0166-218X(98)00067-5</a>","ieee":"H. Edelsbrunner, M. Facello, and J. Liang, “On the definition and the construction of pockets in macromolecules,” <i>Discrete Applied Mathematics</i>, vol. 88, no. 1–3. Elsevier, pp. 83–102, 1998.","ista":"Edelsbrunner H, Facello M, Liang J. 1998. On the definition and the construction of pockets in macromolecules. Discrete Applied Mathematics. 88(1–3), 83–102."},"publist_id":"2114","abstract":[{"text":"The shape of a protein is important for its functions, This includes the location and size of identifiable regions in its complement space. We formally define pockets as regions in the complement with limited accessibility from the outside. Pockets can be efficiently constructed by an algorithm based on alpha complexes. The algorithm is implemented and applied to proteins with known three-dimensional conformations. 1998 Published by Elsevier Science B.V. All rights reserved.","lang":"eng"}],"date_published":"1998-11-09T00:00:00Z","oa_version":"Published Version","year":"1998","volume":88}