{"external_id":{"isi":["000448163900015"]},"author":[{"first_name":"Mara","last_name":"Cucinotta","full_name":"Cucinotta, Mara"},{"first_name":"Silvia","full_name":"Manrique, Silvia","last_name":"Manrique"},{"first_name":"Candela","orcid":"0000-0003-1923-2410","id":"33A3C818-F248-11E8-B48F-1D18A9856A87","last_name":"Cuesta","full_name":"Cuesta, Candela"},{"full_name":"Benková, Eva","last_name":"Benková","first_name":"Eva","orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Ondřej","full_name":"Novák, Ondřej","last_name":"Novák"},{"full_name":"Colombo, Lucia","last_name":"Colombo","first_name":"Lucia"}],"day":"26","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["575"],"type":"journal_article","issue":"21","year":"2018","file_date_updated":"2020-07-14T12:46:25Z","publist_id":"8012","oa_version":"Published Version","acknowledgement":"This work was funded by the Ministry of Education, Youth and Sports of the Czech Republic through the National Program of Sustainability (grant no. LO1204).","department":[{"_id":"EvBe"}],"date_created":"2018-12-11T11:44:19Z","volume":69,"citation":{"ieee":"M. Cucinotta, S. Manrique, C. Cuesta, E. Benková, O. Novák, and L. Colombo, “Cup-shaped Cotyledon1 (CUC1) and CU2 regulate cytokinin homeostasis to determine ovule number in arabidopsis,” <i>Journal of Experimental Botany</i>, vol. 69, no. 21. Oxford University Press, pp. 5169–5176, 2018.","mla":"Cucinotta, Mara, et al. “Cup-Shaped Cotyledon1 (CUC1) and CU2 Regulate Cytokinin Homeostasis to Determine Ovule Number in Arabidopsis.” <i>Journal of Experimental Botany</i>, vol. 69, no. 21, Oxford University Press, 2018, pp. 5169–76, doi:<a href=\"https://doi.org/10.1093/jxb/ery281\">10.1093/jxb/ery281</a>.","ista":"Cucinotta M, Manrique S, Cuesta C, Benková E, Novák O, Colombo L. 2018. Cup-shaped Cotyledon1 (CUC1) and CU2 regulate cytokinin homeostasis to determine ovule number in arabidopsis. Journal of Experimental Botany. 69(21), 5169–5176.","apa":"Cucinotta, M., Manrique, S., Cuesta, C., Benková, E., Novák, O., &#38; Colombo, L. (2018). Cup-shaped Cotyledon1 (CUC1) and CU2 regulate cytokinin homeostasis to determine ovule number in arabidopsis. <i>Journal of Experimental Botany</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/jxb/ery281\">https://doi.org/10.1093/jxb/ery281</a>","ama":"Cucinotta M, Manrique S, Cuesta C, Benková E, Novák O, Colombo L. Cup-shaped Cotyledon1 (CUC1) and CU2 regulate cytokinin homeostasis to determine ovule number in arabidopsis. <i>Journal of Experimental Botany</i>. 2018;69(21):5169-5176. doi:<a href=\"https://doi.org/10.1093/jxb/ery281\">10.1093/jxb/ery281</a>","short":"M. Cucinotta, S. Manrique, C. Cuesta, E. Benková, O. Novák, L. Colombo, Journal of Experimental Botany 69 (2018) 5169–5176.","chicago":"Cucinotta, Mara, Silvia Manrique, Candela Cuesta, Eva Benková, Ondřej Novák, and Lucia Colombo. “Cup-Shaped Cotyledon1 (CUC1) and CU2 Regulate Cytokinin Homeostasis to Determine Ovule Number in Arabidopsis.” <i>Journal of Experimental Botany</i>. Oxford University Press, 2018. <a href=\"https://doi.org/10.1093/jxb/ery281\">https://doi.org/10.1093/jxb/ery281</a>."},"_id":"42","date_published":"2018-07-26T00:00:00Z","isi":1,"article_processing_charge":"No","has_accepted_license":"1","file":[{"checksum":"ca3b6711040b1662488aeb3d1f961f13","creator":"dernst","date_created":"2018-12-17T10:44:16Z","file_id":"5691","relation":"main_file","date_updated":"2020-07-14T12:46:25Z","file_size":1292128,"access_level":"open_access","content_type":"application/pdf","file_name":"2018_JournalExperimBotany_Cucinotta.pdf"}],"page":"5169 - 5176","publication_status":"published","publication":"Journal of Experimental Botany","status":"public","oa":1,"doi":"10.1093/jxb/ery281","title":"Cup-shaped Cotyledon1 (CUC1) and CU2 regulate cytokinin homeostasis to determine ovule number in arabidopsis","publisher":"Oxford University Press","intvolume":"        69","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Seeds derive from ovules upon fertilization and therefore the total number of ovules determines the final seed yield, a fundamental trait in crop plants. Among the factors that co-ordinate the process of ovule formation, the transcription factors CUP-SHAPED COTYLEDON 1 (CUC1) and CUC2 and the hormone cytokinin (CK) have a particularly prominent role. Indeed, the absence of both CUC1 and CUC2 causes a severe reduction in ovule number, a phenotype that can be rescued by CK treatment. In this study, we combined CK quantification with an integrative genome-wide target identification approach to select Arabidopsis genes regulated by CUCs that are also involved in CK metabolism. We focused our attention on the functional characterization of UDP-GLUCOSYL TRANSFERASE 85A3 (UGT85A3) and UGT73C1, which are up-regulated in the absence of CUC1 and CUC2 and encode enzymes able to catalyse CK inactivation by O-glucosylation. Our results demonstrate a role for these UGTs as a link between CUCs and CK homeostasis, and highlight the importance of CUCs and CKs in the determination of seed yield."}],"scopus_import":"1","month":"07","quality_controlled":"1","date_updated":"2023-09-11T12:52:03Z"}