--- res: bibo_abstract: - The discovery of the genetic code was one of the most important advances of modern biology. But there is more to a DNA code than protein sequence; DNA carries signals for splicing, localization, folding, and regulation that are often embedded within the protein-coding sequence. In this issue, Itzkovitz and Alon show that the specific 64-to-20 mapping found in the genetic code may have been optimized for permitting protein-coding regions to carry this extra information and suggest that this property may have evolved as a side benefit of selection to minimize the negative effects of frameshift errors.@eng bibo_authorlist: - foaf_Person: foaf_givenName: Mark Tobias foaf_name: Bollenbach, Mark Tobias foaf_surname: Bollenbach foaf_workInfoHomepage: http://www.librecat.org/personId=3E6DB97A-F248-11E8-B48F-1D18A9856A87 orcid: 0000-0003-4398-476X - foaf_Person: foaf_givenName: Kalin foaf_name: Vetsigian, Kalin foaf_surname: Vetsigian - foaf_Person: foaf_givenName: Roy foaf_name: Kishony, Roy foaf_surname: Kishony bibo_doi: 10.1101/gr.6144007 bibo_issue: '4' bibo_volume: 17 dct_date: 2007^xs_gYear dct_language: eng dct_publisher: Cold Spring Harbor Laboratory Press@ dct_title: Evolution and multilevel optimization of the genetic code@ ...