---
_id: '450'
abstract:
- lang: eng
  text: Understanding the relative importance of heterosis and outbreeding depression
    over multiple generations is a key question in evolutionary biology and is essential
    for identifying appropriate genetic sources for population and ecosystem restoration.
    Here we use 2455 experimental crosses between 12 population pairs of the rare
    perennial plant Rutidosis leptorrhynchoides (Asteraceae) to investigate the multi-generational
    (F1, F2, F3) fitness outcomes of inter-population hybridization. We detected no
    evidence of outbreeding depression, with inter-population hybrids and backcrosses
    showing either similar fitness or significant heterosis for fitness components
    across the three generations. Variation in heterosis among population pairs was
    best explained by characteristics of the foreign source or home population, and
    was greatest when the source population was large, with high genetic diversity
    and low inbreeding, and the home population was small and inbred. Our results
    indicate that the primary consideration for maximizing progeny fitness following
    population augmentation or restoration is the use of seed from large, genetically
    diverse populations.
article_number: '2058'
article_processing_charge: No
author:
- first_name: Melinda
  full_name: Pickup, Melinda
  id: 2C78037E-F248-11E8-B48F-1D18A9856A87
  last_name: Pickup
  orcid: 0000-0001-6118-0541
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: David
  full_name: Rowell, David
  last_name: Rowell
- first_name: Andrew
  full_name: Young, Andrew
  last_name: Young
citation:
  ama: Pickup M, Field D, Rowell D, Young A. Source population characteristics affect
    heterosis following genetic rescue of fragmented plant populations. <i>Proceedings
    of the Royal Society of London Series B Biological Sciences</i>. 2013;280(1750).
    doi:<a href="https://doi.org/10.1098/rspb.2012.2058">10.1098/rspb.2012.2058</a>
  apa: Pickup, M., Field, D., Rowell, D., &#38; Young, A. (2013). Source population
    characteristics affect heterosis following genetic rescue of fragmented plant
    populations. <i>Proceedings of the Royal Society of London Series B Biological
    Sciences</i>. Royal Society. <a href="https://doi.org/10.1098/rspb.2012.2058">https://doi.org/10.1098/rspb.2012.2058</a>
  chicago: Pickup, Melinda, David Field, David Rowell, and Andrew Young. “Source Population
    Characteristics Affect Heterosis Following Genetic Rescue of Fragmented Plant
    Populations.” <i>Proceedings of the Royal Society of London Series B Biological
    Sciences</i>. Royal Society, 2013. <a href="https://doi.org/10.1098/rspb.2012.2058">https://doi.org/10.1098/rspb.2012.2058</a>.
  ieee: M. Pickup, D. Field, D. Rowell, and A. Young, “Source population characteristics
    affect heterosis following genetic rescue of fragmented plant populations,” <i>Proceedings
    of the Royal Society of London Series B Biological Sciences</i>, vol. 280, no.
    1750. Royal Society, 2013.
  ista: Pickup M, Field D, Rowell D, Young A. 2013. Source population characteristics
    affect heterosis following genetic rescue of fragmented plant populations. Proceedings
    of the Royal Society of London Series B Biological Sciences. 280(1750), 2058.
  mla: Pickup, Melinda, et al. “Source Population Characteristics Affect Heterosis
    Following Genetic Rescue of Fragmented Plant Populations.” <i>Proceedings of the
    Royal Society of London Series B Biological Sciences</i>, vol. 280, no. 1750,
    2058, Royal Society, 2013, doi:<a href="https://doi.org/10.1098/rspb.2012.2058">10.1098/rspb.2012.2058</a>.
  short: M. Pickup, D. Field, D. Rowell, A. Young, Proceedings of the Royal Society
    of London Series B Biological Sciences 280 (2013).
corr_author: '1'
date_created: 2018-12-11T11:46:32Z
date_published: 2013-01-07T00:00:00Z
date_updated: 2026-08-12T06:25:53Z
day: '07'
department:
- _id: NiBa
doi: 10.1098/rspb.2012.2058
external_id:
  isi:
  - '000311943100012'
  pmid:
  - '23173202'
fulldoi: https://doi.org/10.1098/rspb.2012.2058
intvolume: '       280'
isi: 1
issue: '1750'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574427/
month: '01'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_status: published
publisher: Royal Society
publist_id: '7372'
quality_controlled: '1'
status: public
title: Source population characteristics affect heterosis following genetic rescue
  of fragmented plant populations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 280
year: '2013'
...