---
res:
  bibo_abstract:
  - Temperate bacteriophages integrate in bacterial genomes as prophages and represent
    an important source of genetic variation for bacterial evolution, frequently transmitting
    fitness-augmenting genes such as toxins responsible for virulence of major pathogens.
    However, only a fraction of bacteriophage infections are lysogenic and lead to
    prophage acquisition, whereas the majority are lytic and kill the infected bacteria.
    Unless able to discriminate lytic from lysogenic infections, mechanisms of immunity
    to bacteriophages are expected to act as a double-edged sword and increase the
    odds of survival at the cost of depriving bacteria of potentially beneficial prophages.
    We show that although restriction-modification systems as mechanisms of innate
    immunity prevent both lytic and lysogenic infections indiscriminately in individual
    bacteria, they increase the number of prophage-acquiring individuals at the population
    level. We find that this counterintuitive result is a consequence of phage-host
    population dynamics, in which restriction-modification systems delay infection
    onset until bacteria reach densities at which the probability of lysogeny increases.
    These results underscore the importance of population-level dynamics as a key
    factor modulating costs and benefits of immunity to temperate bacteriophages@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Maros
      foaf_name: Pleska, Maros
      foaf_surname: Pleska
      foaf_workInfoHomepage: http://www.librecat.org/personId=4569785E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-7460-7479
  - foaf_Person:
      foaf_givenName: Moritz
      foaf_name: Lang, Moritz
      foaf_surname: Lang
      foaf_workInfoHomepage: http://www.librecat.org/personId=29E0800A-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Dominik
      foaf_name: Refardt, Dominik
      foaf_surname: Refardt
  - foaf_Person:
      foaf_givenName: Bruce
      foaf_name: Levin, Bruce
      foaf_surname: Levin
  - foaf_Person:
      foaf_givenName: Calin C
      foaf_name: Guet, Calin C
      foaf_surname: Guet
      foaf_workInfoHomepage: http://www.librecat.org/personId=47F8433E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-6220-2052
  bibo_doi: 10.1038/s41559-017-0424-z
  bibo_issue: '2'
  bibo_volume: 2
  dct_date: 2018^xs_gYear
  dct_identifier:
  - UT:000426516400027
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: Phage-host population dynamics promotes prophage acquisition in bacteria
    with innate immunity@
...