Limiting shapes of confined lipid vesicles Kavcic, Bor ; https://orcid.org/0000-0001-6041-254X Sakashita, A. Noguchi, H. Ziherl, P. ddc:530 We theoretically study the shapes of lipid vesicles confined to a spherical cavity, elaborating a framework based on the so-called limiting shapes constructed from geometrically simple structural elements such as double-membrane walls and edges. Partly inspired by numerical results, the proposed non-compartmentalized and compartmentalized limiting shapes are arranged in the bilayer-couple phase diagram which is then compared to its free-vesicle counterpart. We also compute the area-difference-elasticity phase diagram of the limiting shapes and we use it to interpret shape transitions experimentally observed in vesicles confined within another vesicle. The limiting-shape framework may be generalized to theoretically investigate the structure of certain cell organelles such as the mitochondrion. Royal Society of Chemistry 2019 info:eu-repo/semantics/article doc-type:article text http://purl.org/coar/resource_type/c_2df8fbb1 https://research-explorer.ista.ac.at/record/5817 https://research-explorer.ista.ac.at/download/5817/8641 Kavcic B, Sakashita A, Noguchi H, Ziherl P. Limiting shapes of confined lipid vesicles. <i>Soft Matter</i>. 2019;15(4):602-614. doi:<a href="https://doi.org/10.1039/c8sm01956h">10.1039/c8sm01956h</a> eng info:eu-repo/semantics/altIdentifier/doi/10.1039/c8sm01956h info:eu-repo/semantics/altIdentifier/issn/1744-683X info:eu-repo/semantics/altIdentifier/e-issn/1744-6848 info:eu-repo/semantics/altIdentifier/wos/000457329700003 info:eu-repo/semantics/altIdentifier/pmid/30629082 https://creativecommons.org/licenses/by-nc-nd/3.0/ info:eu-repo/semantics/openAccess