---
res:
  bibo_abstract:
  - "This dataset contains the supplementary data for the research paper \"Haploinsufficiency
    of the intellectual disability gene SETD5 disturbs developmental gene expression
    and cognition\".\r\n\r\nThe contained files have the following content:\r\n'Supplementary
    Figures.pdf'\r\n\tAdditional figures (as referenced in the paper).\r\n'Supplementary
    Table 1. Statistics.xlsx'\r\n\tDetails on statistical tests performed in the paper.\r\n'Supplementary
    Table 2. Differentially expressed gene analysis.xlsx'\r\n\tResults for the differential
    gene expression analysis for embryonic (E9.5; analysis with edgeR) and in vitro
    (ESCs, EBs, NPCs; analysis with DESeq2) samples.\r\n'Supplementary Table 3. Gene
    Ontology (GO) term enrichment analysis.xlsx'\r\n\tResults for the GO term enrichment
    analysis for differentially expressed genes in embryonic (GO E9.5) and in vitro
    (GO ESC, GO EBs, GO NPCs) samples. Differentially expressed genes for in vitro
    samples were split into upregulated and downregulated genes (up/down) and the
    analysis was performed on each subset (e.g. GO ESC up / GO ESC down).\r\n'Supplementary
    Table 4. Differentially expressed gene analysis for CFC samples.xlsx'\r\n\tResults
    for the differential gene expression analysis for samples from adult mice before
    (HC - Homecage) and 1h and 3h after contextual fear conditioning (1h and 3h, respectively).
    Each sheet shows the results for a different comparison. Sheets 1-3 show results
    for comparisons between timepoints for wild type (WT) samples only and sheets
    4-6 for the same comparisons in mutant (Het) samples. Sheets 7-9 show results
    for comparisons between genotypes at each time point and sheet 10 contains the
    results for the analysis of differential expression trajectories between wild
    type and mutant.\r\n'Supplementary Table 5. Cluster identification.xlsx'\r\n\tResults
    for k-means clustering of genes by expression. Sheet 1 shows clustering of just
    the genes with significantly different expression trajectories between genotypes.
    Sheet 2 shows clustering of all genes that are significantly differentially expressed
    in any of the comparisons (includes also genes with same trajectories).\r\n'Supplementary
    Table 6. GO term cluster analysis.xlsx'\r\n\tResults for the GO term enrichment
    analysis and EWCE analysis for enrichment of cell type specific genes for each
    cluster identified by clustering genes with different expression trajectories
    (see Table S5, sheet 1).\r\n'Supplementary Table 7. Setd5 mass spectrometry results.xlsx'\r\n\tResults
    showing proteins interacting with Setd5 as identified by mass spectrometry. Sheet
    1 shows protein protein interaction data generated from these results (combined
    with data from the STRING database. Sheet 2 shows the results of the statistical
    analysis with limma.\r\n'Supplementary Table 8. PolII ChIP-seq analysis.xlsx'\r\n\tResults
    for the Chip-Seq analysis for binding of RNA polymerase II (PolII). Sheet 1 shows
    results for differential binding of PolII at the transcription start site (TSS)
    between genotypes and sheets 2+3 show the corresponding GO enrichment analysis
    for these differentially bound genes. Sheet 4 shows RNAseq counts for genes with
    increased binding of PolII at the TSS.@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Christoph
      foaf_name: Dotter, Christoph
      foaf_surname: Dotter
      foaf_workInfoHomepage: http://www.librecat.org/personId=4C66542E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-9033-9096
  - foaf_Person:
      foaf_givenName: Gaia
      foaf_name: Novarino, Gaia
      foaf_surname: Novarino
      foaf_workInfoHomepage: http://www.librecat.org/personId=3E57A680-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-7673-7178
  bibo_doi: 10.15479/AT:ISTA:6074
  dct_date: 2019^xs_gYear
  dct_publisher: Institute of Science and Technology Austria@
  dct_title: Supplementary data for the research paper "Haploinsufficiency of the
    intellectual disability gene SETD5 disturbs developmental gene expression and
    cognition"@
...