---
res:
  bibo_abstract:
  - Insects are exposed to a variety of potential pathogens in their environment,
    many of which can severely impact fitness and health. Consequently, hosts have
    evolved resistance and tolerance strategies to suppress or cope with infections.
    Hosts utilizing resistance improve fitness by clearing or reducing pathogen loads,
    and hosts utilizing tolerance reduce harmful fitness effects per pathogen load.
    To understand variation in, and selective pressures on, resistance and tolerance,
    we asked to what degree they are shaped by host genetic background, whether plasticity
    in these responses depends upon dietary environment, and whether there are interactions
    between these two factors. Females from ten wild-type Drosophila melanogaster
    genotypes were kept on high- or low-protein (yeast) diets and infected with one
    of two opportunistic bacterial pathogens, Lactococcus lactis or Pseudomonas entomophila.
    We measured host resistance as the inverse of bacterial load in the early infection
    phase. The relationship (slope) between fly fecundity and individual-level bacteria
    load provided our fecundity tolerance measure. Genotype and dietary yeast determined
    host fecundity and strongly affected survival after infection with pathogenic
    P. entomophila. There was considerable genetic variation in host resistance, a
    commonly found phenomenon resulting from for example varying resistance costs
    or frequency-dependent selection. Despite this variation and the reproductive
    cost of higher P. entomophila loads, fecundity tolerance did not vary across genotypes.
    The absence of genetic variation in tolerance may suggest that at this early infection
    stage, fecundity tolerance is fixed or that any evolved tolerance mechanisms are
    not expressed under these infection conditions.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Megan
      foaf_name: Kutzer, Megan
      foaf_surname: Kutzer
      foaf_workInfoHomepage: http://www.librecat.org/personId=29D0B332-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8696-6978
  - foaf_Person:
      foaf_givenName: Joachim
      foaf_name: Kurtz, Joachim
      foaf_surname: Kurtz
  - foaf_Person:
      foaf_givenName: Sophie
      foaf_name: Armitage, Sophie
      foaf_surname: Armitage
  bibo_doi: 10.1111/jeb.13211
  bibo_issue: '1'
  bibo_volume: 31
  dct_date: 2018^xs_gYear
  dct_identifier:
  - UT:000419307000014
  dct_isPartOf:
  - http://id.crossref.org/issn/1010-061X
  - http://id.crossref.org/issn/1420-9101
  dct_language: eng
  dct_publisher: Wiley@
  dct_title: Genotype and diet affect resistance, survival, and fecundity but not
    fecundity tolerance@
  fabio_hasPubmedId: '29150962'
...