---
res:
  bibo_abstract:
  - Aberrant display of the truncated core1 O-glycan T-antigen is a common feature
    of human cancer cells that correlates with metastasis. Here we show that T-antigen
    in Drosophila melanogaster macrophages is involved in their developmentally programmed
    tissue invasion. Higher macrophage T-antigen levels require an atypical major
    facilitator superfamily (MFS) member that we named Minerva which enables macrophage
    dissemination and invasion. We characterize for the first time the T and Tn glycoform
    O-glycoproteome of the Drosophila melanogaster embryo, and determine that Minerva
    increases the presence of T-antigen on proteins in pathways previously linked
    to cancer, most strongly on the sulfhydryl oxidase Qsox1 which we show is required
    for macrophage tissue entry. Minerva’s vertebrate ortholog, MFSD1, rescues the
    minerva mutant’s migration and T-antigen glycosylation defects. We thus identify
    a key conserved regulator that orchestrates O-glycosylation on a protein subset
    to activate a program governing migration steps important for both development
    and cancer metastasis.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Katarina
      foaf_name: Valosková, Katarina
      foaf_surname: Valosková
      foaf_workInfoHomepage: http://www.librecat.org/personId=46F146FC-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-7926-0221
  - foaf_Person:
      foaf_givenName: Julia
      foaf_name: Biebl, Julia
      foaf_surname: Biebl
      foaf_workInfoHomepage: http://www.librecat.org/personId=3CCBB46E-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Marko
      foaf_name: Roblek, Marko
      foaf_surname: Roblek
      foaf_workInfoHomepage: http://www.librecat.org/personId=3047D808-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-9588-1389
  - foaf_Person:
      foaf_givenName: Shamsi
      foaf_name: Emtenani, Shamsi
      foaf_surname: Emtenani
      foaf_workInfoHomepage: http://www.librecat.org/personId=49D32318-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-6981-6938
  - foaf_Person:
      foaf_givenName: Attila
      foaf_name: György, Attila
      foaf_surname: György
      foaf_workInfoHomepage: http://www.librecat.org/personId=3BCEDBE0-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-1819-198X
  - foaf_Person:
      foaf_givenName: Michaela
      foaf_name: Misova, Michaela
      foaf_surname: Misova
      foaf_workInfoHomepage: http://www.librecat.org/personId=495A3C32-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-2427-6856
  - foaf_Person:
      foaf_givenName: Aparna
      foaf_name: Ratheesh, Aparna
      foaf_surname: Ratheesh
      foaf_workInfoHomepage: http://www.librecat.org/personId=2F064CFE-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-7190-0776
  - foaf_Person:
      foaf_givenName: Patricia
      foaf_name: Dos Reis Rodrigues, Patricia
      foaf_surname: Dos Reis Rodrigues
      foaf_workInfoHomepage: http://www.librecat.org/personId=26E95904-5160-11E9-9C0B-C5B0DC97E90F
    orcid: 0000-0003-1681-508X
  - foaf_Person:
      foaf_givenName: Katerina
      foaf_name: Shkarina, Katerina
      foaf_surname: Shkarina
  - foaf_Person:
      foaf_givenName: Ida Signe Bohse
      foaf_name: Larsen, Ida Signe Bohse
      foaf_surname: Larsen
  - foaf_Person:
      foaf_givenName: Sergey Y
      foaf_name: Vakhrushev, Sergey Y
      foaf_surname: Vakhrushev
  - foaf_Person:
      foaf_givenName: Henrik
      foaf_name: Clausen, Henrik
      foaf_surname: Clausen
  - foaf_Person:
      foaf_givenName: Daria E
      foaf_name: Siekhaus, Daria E
      foaf_surname: Siekhaus
      foaf_workInfoHomepage: http://www.librecat.org/personId=3D224B9E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8323-8353
  bibo_doi: 10.7554/elife.41801
  bibo_volume: 8
  dct_date: 2019^xs_gYear
  dct_identifier:
  - UT:000462530200001
  dct_isPartOf:
  - http://id.crossref.org/issn/2050-084X
  dct_language: eng
  dct_publisher: eLife Sciences Publications@
  dct_title: A conserved major facilitator superfamily member orchestrates a subset
    of O-glycosylation to aid macrophage tissue invasion@
...