---
res:
  bibo_abstract:
  - The plant hormone auxin has crucial roles in almost all aspects of plant growth
    and development. Concentrations of auxin vary across different tissues, mediating
    distinct developmental outcomes and contributing to the functional diversity of
    auxin. However, the mechanisms that underlie these activities are poorly understood.
    Here we identify an auxin signalling mechanism, which acts in parallel to the
    canonical auxin pathway based on the transport inhibitor response1 (TIR1) and
    other auxin receptor F-box (AFB) family proteins (TIR1/AFB receptors)1,2, that
    translates levels of cellular auxin to mediate differential growth during apical-hook
    development. This signalling mechanism operates at the concave side of the apical
    hook, and involves auxin-mediated C-terminal cleavage of transmembrane kinase
    1 (TMK1). The cytosolic and nucleus-translocated C terminus of TMK1 specifically
    interacts with and phosphorylates two non-canonical transcriptional repressors
    of the auxin or indole-3-acetic acid (Aux/IAA) family (IAA32 and IAA34), thereby
    regulating ARF transcription factors. In contrast to the degradation of Aux/IAA
    transcriptional repressors in the canonical pathway, the newly identified mechanism
    stabilizes the non-canonical IAA32 and IAA34 transcriptional repressors to regulate
    gene expression and ultimately inhibit growth. The auxin–TMK1 signalling pathway
    originates at the cell surface, is triggered by high levels of auxin and shares
    a partially overlapping set of transcription factors with the TIR1/AFB signalling
    pathway. This allows distinct interpretations of different concentrations of cellular
    auxin, and thus enables this versatile signalling molecule to mediate complex
    developmental outcomes.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Min
      foaf_name: Cao, Min
      foaf_surname: Cao
  - foaf_Person:
      foaf_givenName: Rong
      foaf_name: Chen, Rong
      foaf_surname: Chen
  - foaf_Person:
      foaf_givenName: Pan
      foaf_name: Li, Pan
      foaf_surname: Li
  - foaf_Person:
      foaf_givenName: Yongqiang
      foaf_name: Yu, Yongqiang
      foaf_surname: Yu
  - foaf_Person:
      foaf_givenName: Rui
      foaf_name: Zheng, Rui
      foaf_surname: Zheng
  - foaf_Person:
      foaf_givenName: Danfeng
      foaf_name: Ge, Danfeng
      foaf_surname: Ge
  - foaf_Person:
      foaf_givenName: Wei
      foaf_name: Zheng, Wei
      foaf_surname: Zheng
  - foaf_Person:
      foaf_givenName: Xuhui
      foaf_name: Wang, Xuhui
      foaf_surname: Wang
  - foaf_Person:
      foaf_givenName: Yangtao
      foaf_name: Gu, Yangtao
      foaf_surname: Gu
  - foaf_Person:
      foaf_givenName: Zuzana
      foaf_name: Gelová, Zuzana
      foaf_surname: Gelová
      foaf_workInfoHomepage: http://www.librecat.org/personId=0AE74790-0E0B-11E9-ABC7-1ACFE5697425
    orcid: 0000-0003-4783-1752
  - foaf_Person:
      foaf_givenName: Jiří
      foaf_name: Friml, Jiří
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  - foaf_Person:
      foaf_givenName: Heng
      foaf_name: Zhang, Heng
      foaf_surname: Zhang
  - foaf_Person:
      foaf_givenName: Renyi
      foaf_name: Liu, Renyi
      foaf_surname: Liu
  - foaf_Person:
      foaf_givenName: Jun
      foaf_name: He, Jun
      foaf_surname: He
  - foaf_Person:
      foaf_givenName: Tongda
      foaf_name: Xu, Tongda
      foaf_surname: Xu
  bibo_doi: 10.1038/s41586-019-1069-7
  bibo_volume: 568
  dct_date: 2019^xs_gYear
  dct_identifier:
  - UT:000464412700050
  dct_isPartOf:
  - http://id.crossref.org/issn/0028-0836
  - http://id.crossref.org/issn/1476-4687
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: TMK1-mediated auxin signalling regulates differential growth of the apical
    hook@
  fabio_hasPubmedId: '30944466'
...