---
_id: '6496'
abstract:
- lang: eng
  text: We report the switching behavior of the full bacterial flagellum system that
    includes the filament and the motor in wild-type Escherichia coli cells. In sorting
    the motor behavior by the clockwise bias, we find that the distributions of the
    clockwise (CW) and counterclockwise (CCW) intervals are either exponential or
    nonexponential with long tails. At low bias, CW intervals are exponentially distributed
    and CCW intervals exhibit long tails. At intermediate CW bias (0.5) both CW and
    CCW intervals are mainly exponentially distributed. A simple model suggests that
    these two distinct switching behaviors are governed by the presence of signaling
    noise within the chemotaxis network. Low noise yields exponentially distributed
    intervals, whereas large noise yields nonexponential behavior with long tails.
    These drastically different motor statistics may play a role in optimizing bacterial
    behavior for a wide range of environmental conditions.
article_processing_charge: No
author:
- first_name: Heungwon
  full_name: Park, Heungwon
  last_name: Park
- first_name: Panos
  full_name: Oikonomou, Panos
  last_name: Oikonomou
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
- first_name: Philippe
  full_name: Cluzel, Philippe
  last_name: Cluzel
citation:
  ama: Park H, Oikonomou P, Guet CC, Cluzel P. Noise underlies switching behavior
    of the bacterial flagellum. <i>Biophysical Journal</i>. 2011;101(10):2336-2340.
    doi:<a href="https://doi.org/10.1016/j.bpj.2011.09.040">10.1016/j.bpj.2011.09.040</a>
  apa: Park, H., Oikonomou, P., Guet, C. C., &#38; Cluzel, P. (2011). Noise underlies
    switching behavior of the bacterial flagellum. <i>Biophysical Journal</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.bpj.2011.09.040">https://doi.org/10.1016/j.bpj.2011.09.040</a>
  chicago: Park, Heungwon, Panos Oikonomou, Calin C Guet, and Philippe Cluzel. “Noise
    Underlies Switching Behavior of the Bacterial Flagellum.” <i>Biophysical Journal</i>.
    Elsevier, 2011. <a href="https://doi.org/10.1016/j.bpj.2011.09.040">https://doi.org/10.1016/j.bpj.2011.09.040</a>.
  ieee: H. Park, P. Oikonomou, C. C. Guet, and P. Cluzel, “Noise underlies switching
    behavior of the bacterial flagellum,” <i>Biophysical Journal</i>, vol. 101, no.
    10. Elsevier, pp. 2336–2340, 2011.
  ista: Park H, Oikonomou P, Guet CC, Cluzel P. 2011. Noise underlies switching behavior
    of the bacterial flagellum. Biophysical Journal. 101(10), 2336–2340.
  mla: Park, Heungwon, et al. “Noise Underlies Switching Behavior of the Bacterial
    Flagellum.” <i>Biophysical Journal</i>, vol. 101, no. 10, Elsevier, 2011, pp.
    2336–40, doi:<a href="https://doi.org/10.1016/j.bpj.2011.09.040">10.1016/j.bpj.2011.09.040</a>.
  short: H. Park, P. Oikonomou, C.C. Guet, P. Cluzel, Biophysical Journal 101 (2011)
    2336–2340.
date_created: 2019-05-28T11:54:29Z
date_published: 2011-11-16T00:00:00Z
date_updated: 2025-09-30T09:26:28Z
day: '16'
department:
- _id: CaGu
doi: 10.1016/j.bpj.2011.09.040
external_id:
  isi:
  - '000297143500008'
  pmid:
  - '22098731'
intvolume: '       101'
isi: 1
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218319/
month: '11'
oa: 1
oa_version: Published Version
page: 2336-2340
pmid: 1
publication: Biophysical Journal
publication_identifier:
  issn:
  - 0006-3495
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Noise underlies switching behavior of the bacterial flagellum
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 101
year: '2011'
...