---
res:
  bibo_abstract:
  - Growing microtubules are protected from depolymerization by the presence of a
    GTP or GDP/Pi cap. End-binding proteins of the EB1 family bind to the stabilizing
    cap, allowing monitoring of its size in real time. The cap size has been shown
    to correlate with instantaneous microtubule stability. Here we have quantitatively
    characterized the properties of cap size fluctuations during steadystate growth
    and have developed a theory predicting their timescale and amplitude from the
    kinetics of microtubule growth and cap maturation. In contrast to growth speed
    fluctuations, cap size fluctuations show a characteristic timescale, which is
    defined by the lifetime of the cap sites. Growth fluctuations affect the amplitude
    of cap size fluctuations; however, cap size does not affect growth speed, indicating
    that microtubules are far from instability during most of their time of growth.
    Our theory provides the basis for a quantitative understanding of microtubule
    stability fluctuations during steady-state growth.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Jamie
      foaf_name: Rickman, Jamie
      foaf_surname: Rickman
  - foaf_Person:
      foaf_givenName: Christian F
      foaf_name: Düllberg, Christian F
      foaf_surname: Düllberg
      foaf_workInfoHomepage: http://www.librecat.org/personId=459064DC-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-6335-9748
  - foaf_Person:
      foaf_givenName: Nicholas
      foaf_name: Cade, Nicholas
      foaf_surname: Cade
  - foaf_Person:
      foaf_givenName: Lewis
      foaf_name: Griffin, Lewis
      foaf_surname: Griffin
  - foaf_Person:
      foaf_givenName: Thomas
      foaf_name: Surrey, Thomas
      foaf_surname: Surrey
  bibo_doi: 10.1073/pnas.1620274114
  bibo_issue: '13'
  bibo_volume: 114
  dct_date: 2017^xs_gYear
  dct_identifier:
  - UT:000397607300065
  dct_isPartOf:
  - http://id.crossref.org/issn/0027-8424
  dct_language: eng
  dct_publisher: National Academy of Sciences@
  dct_title: Steady state EB cap size fluctuations are determined by stochastic microtubule
    growth and maturation@
  fabio_hasPubmedId: '28280102'
...