---
_id: '6627'
abstract:
- lang: eng
  text: Cortical microtubule arrays in elongating epidermal cells in both the root
    and stem of plants have the propensity of dynamic reorientations that are correlated
    with the activation or inhibition of growth. Factors regulating plant growth,
    among them the hormone auxin, have been recognized as regulators of microtubule
    array orientations. Some previous work in the field has aimed at elucidating the
    causal relationship between cell growth, the signaling of auxin or other growth-regulating
    factors, and microtubule array reorientations, with various conclusions. Here,
    we revisit this problem of causality with a comprehensive set of experiments in
    Arabidopsis thaliana, using the now available pharmacological and genetic tools.
    We use isolated, auxin-depleted hypocotyls, an experimental system allowing for
    full control of both growth and auxin signaling. We demonstrate that reorientation
    of microtubules is not directly triggered by an auxin signal during growth activation.
    Instead, reorientation is triggered by the activation of the growth process itself
    and is auxin-independent in its nature. We discuss these findings in the context
    of previous relevant work, including that on the mechanical regulation of microtubule
    array orientation.
article_number: '3337'
article_processing_charge: Yes
article_type: original
author:
- first_name: Maciek
  full_name: Adamowski, Maciek
  id: 45F536D2-F248-11E8-B48F-1D18A9856A87
  last_name: Adamowski
  orcid: 0000-0001-6463-5257
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Adamowski M, Li L, Friml J. Reorientation of cortical microtubule arrays in
    the hypocotyl of arabidopsis thaliana is induced by the cell growth process and
    independent of auxin signaling. <i>International Journal of Molecular Sciences</i>.
    2019;20(13). doi:<a href="https://doi.org/10.3390/ijms20133337">10.3390/ijms20133337</a>
  apa: Adamowski, M., Li, L., &#38; Friml, J. (2019). Reorientation of cortical microtubule
    arrays in the hypocotyl of arabidopsis thaliana is induced by the cell growth
    process and independent of auxin signaling. <i>International Journal of Molecular
    Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms20133337">https://doi.org/10.3390/ijms20133337</a>
  chicago: Adamowski, Maciek, Lanxin Li, and Jiří Friml. “Reorientation of Cortical
    Microtubule Arrays in the Hypocotyl of Arabidopsis Thaliana Is Induced by the
    Cell Growth Process and Independent of Auxin Signaling.” <i>International Journal
    of Molecular Sciences</i>. MDPI, 2019. <a href="https://doi.org/10.3390/ijms20133337">https://doi.org/10.3390/ijms20133337</a>.
  ieee: M. Adamowski, L. Li, and J. Friml, “Reorientation of cortical microtubule
    arrays in the hypocotyl of arabidopsis thaliana is induced by the cell growth
    process and independent of auxin signaling,” <i>International Journal of Molecular
    Sciences</i>, vol. 20, no. 13. MDPI, 2019.
  ista: Adamowski M, Li L, Friml J. 2019. Reorientation of cortical microtubule arrays
    in the hypocotyl of arabidopsis thaliana is induced by the cell growth process
    and independent of auxin signaling. International Journal of Molecular Sciences.
    20(13), 3337.
  mla: Adamowski, Maciek, et al. “Reorientation of Cortical Microtubule Arrays in
    the Hypocotyl of Arabidopsis Thaliana Is Induced by the Cell Growth Process and
    Independent of Auxin Signaling.” <i>International Journal of Molecular Sciences</i>,
    vol. 20, no. 13, 3337, MDPI, 2019, doi:<a href="https://doi.org/10.3390/ijms20133337">10.3390/ijms20133337</a>.
  short: M. Adamowski, L. Li, J. Friml, International Journal of Molecular Sciences
    20 (2019).
corr_author: '1'
date_created: 2019-07-11T12:00:32Z
date_published: 2019-07-07T00:00:00Z
date_updated: 2026-04-16T22:33:23Z
day: '07'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.3390/ijms20133337
ec_funded: 1
external_id:
  isi:
  - '000477041100221'
  pmid:
  - '31284661'
file:
- access_level: open_access
  checksum: dd9d1cbb933a72ceb666c9667890ac51
  content_type: application/pdf
  creator: dernst
  date_created: 2019-07-17T06:17:15Z
  date_updated: 2020-07-14T12:47:34Z
  file_id: '6645'
  file_name: 2019_JournalMolecularScience_Adamowski.pdf
  file_size: 3330291
  relation: main_file
file_date_updated: 2020-07-14T12:47:34Z
has_accepted_license: '1'
intvolume: '        20'
isi: 1
issue: '13'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: International Journal of Molecular Sciences
publication_identifier:
  eissn:
  - 1422-0067
publication_status: published
publisher: MDPI
quality_controlled: '1'
related_material:
  record:
  - id: '10083'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Reorientation of cortical microtubule arrays in the hypocotyl of arabidopsis
  thaliana is induced by the cell growth process and independent of auxin signaling
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 20
year: '2019'
...