---
res:
  bibo_abstract:
  - Trafficking cells frequently transmigrate through epithelial and endothelial monolayers.
    How monolayers cooperate with the penetrating cells to support their transit is
    poorly understood. We studied dendritic cell (DC) entry into lymphatic capillaries
    as a model system for transendothelial migration. We find that the chemokine CCL21,
    which is the decisive guidance cue for intravasation, mainly localizes in the
    trans-Golgi network and intracellular vesicles of lymphatic endothelial cells.
    Upon DC transmigration, these Golgi deposits disperse and CCL21 becomes extracellularly
    enriched at the sites of endothelial cell-cell junctions. When we reconstitute
    the transmigration process in vitro, we find that secretion of CCL21-positive
    vesicles is triggered by a DC contact-induced calcium signal, and selective calcium
    chelation in lymphatic endothelium attenuates transmigration. Altogether, our
    data demonstrate a chemokine-mediated feedback between DCs and lymphatic endothelium,
    which facilitates transendothelial migration.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Kari
      foaf_name: Vaahtomeri, Kari
      foaf_surname: Vaahtomeri
      foaf_workInfoHomepage: http://www.librecat.org/personId=368EE576-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-7829-3518
  - foaf_Person:
      foaf_givenName: Markus
      foaf_name: Brown, Markus
      foaf_surname: Brown
      foaf_workInfoHomepage: http://www.librecat.org/personId=3DAB9AFC-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Robert
      foaf_name: Hauschild, Robert
      foaf_surname: Hauschild
      foaf_workInfoHomepage: http://www.librecat.org/personId=4E01D6B4-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-9843-3522
  - foaf_Person:
      foaf_givenName: Ingrid
      foaf_name: De Vries, Ingrid
      foaf_surname: De Vries
      foaf_workInfoHomepage: http://www.librecat.org/personId=4C7D837E-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Alexander F
      foaf_name: Leithner, Alexander F
      foaf_surname: Leithner
      foaf_workInfoHomepage: http://www.librecat.org/personId=3B1B77E4-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-1073-744X
  - foaf_Person:
      foaf_givenName: Matthias
      foaf_name: Mehling, Matthias
      foaf_surname: Mehling
      foaf_workInfoHomepage: http://www.librecat.org/personId=3C23B994-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8599-1226
  - foaf_Person:
      foaf_givenName: Walter
      foaf_name: Kaufmann, Walter
      foaf_surname: Kaufmann
      foaf_workInfoHomepage: http://www.librecat.org/personId=3F99E422-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-9735-5315
  - foaf_Person:
      foaf_givenName: Michael K
      foaf_name: Sixt, Michael K
      foaf_surname: Sixt
      foaf_workInfoHomepage: http://www.librecat.org/personId=41E9FBEA-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-6620-9179
  bibo_doi: 10.1016/j.celrep.2017.04.027
  bibo_issue: '5'
  bibo_volume: 19
  dct_date: 2017^xs_gYear
  dct_identifier:
  - UT:000402124100002
  dct_isPartOf:
  - http://id.crossref.org/issn/2211-1247
  dct_language: eng
  dct_publisher: Cell Press@
  dct_title: Locally triggered release of the chemokine CCL21 promotes dendritic cell
    transmigration across lymphatic endothelia@
...