---
res:
  bibo_abstract:
  - "Background\r\n\r\nChlamydia are ancient intracellular pathogens with reduced,
    though strikingly conserved genome. Despite their parasitic lifestyle and isolated
    intracellular environment, these bacteria managed to avoid accumulation of deleterious
    mutations leading to subsequent genome degradation characteristic for many parasitic
    bacteria.\r\nResults\r\n\r\nWe report pan-genomic analysis of sixteen species
    from genus Chlamydia including identification and functional annotation of orthologous
    genes, and characterization of gene gains, losses, and rearrangements. We demonstrate
    the overall genome stability of these bacteria as indicated by a large fraction
    of common genes with conserved genomic locations. On the other hand, extreme evolvability
    is confined to several paralogous gene families such as polymorphic membrane proteins
    and phospholipase D, and likely is caused by the pressure from the host immune
    system.\r\nConclusions\r\n\r\nThis combination of a large, conserved core genome
    and a small, evolvable periphery likely reflect the balance between the selective
    pressure towards genome reduction and the need to adapt to escape from the host
    immunity.@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Olga M.
      foaf_name: Sigalova, Olga M.
      foaf_surname: Sigalova
  - foaf_Person:
      foaf_givenName: Andrei V.
      foaf_name: Chaplin, Andrei V.
      foaf_surname: Chaplin
  - foaf_Person:
      foaf_givenName: Olga
      foaf_name: Bochkareva, Olga
      foaf_surname: Bochkareva
      foaf_workInfoHomepage: http://www.librecat.org/personId=C4558D3C-6102-11E9-A62E-F418E6697425
    orcid: 0000-0003-1006-6639
  - foaf_Person:
      foaf_givenName: Pavel V.
      foaf_name: Shelyakin, Pavel V.
      foaf_surname: Shelyakin
  - foaf_Person:
      foaf_givenName: Vsevolod A.
      foaf_name: Filaretov, Vsevolod A.
      foaf_surname: Filaretov
  - foaf_Person:
      foaf_givenName: Evgeny E.
      foaf_name: Akkuratov, Evgeny E.
      foaf_surname: Akkuratov
  - foaf_Person:
      foaf_givenName: Valentina
      foaf_name: Burskaia, Valentina
      foaf_surname: Burskaia
  - foaf_Person:
      foaf_givenName: Mikhail S.
      foaf_name: Gelfand, Mikhail S.
      foaf_surname: Gelfand
  bibo_doi: 10.1186/s12864-019-6059-5
  bibo_issue: '1'
  bibo_volume: 20
  dct_date: 2019^xs_gYear
  dct_identifier:
  - UT:000485256100001
  dct_isPartOf:
  - http://id.crossref.org/issn/1471-2164
  dct_language: eng
  dct_publisher: BioMed Central@
  dct_title: Chlamydia pan-genomic analysis reveals balance between host adaptation
    and selective pressure to genome reduction@
...