---
res:
  bibo_abstract:
  - A hippocampal mossy fiber synapse has a complex structure and is implicated in
    learning and memory. In this synapse, the mossy fiber boutons attach to the dendritic
    shaft by puncta adherentia junctions and wrap around a multiply-branched spine,
    forming synaptic junctions. We have recently shown using transmission electron
    microscopy, immunoelectron microscopy and serial block face-scanning electron
    microscopy that atypical puncta adherentia junctions are formed in the afadin-deficient
    mossy fiber synapse and that the complexity of postsynaptic spines and mossy fiber
    boutons, the number of spine heads, the area of postsynaptic densities and the
    density of synaptic vesicles docked to active zones are decreased in the afadin-deficient
    synapse. We investigated here the roles of afadin in the functional differentiations
    of the mossy fiber synapse using the afadin-deficient mice. The electrophysiological
    studies showed that both the release probability of glutamate and the postsynaptic
    responsiveness to glutamate were markedly reduced, but not completely lost, in
    the afadin-deficient mossy fiber synapse, whereas neither long-term potentiation
    nor long-term depression was affected. These results indicate that afadin plays
    roles in the functional differentiations of the presynapse and the postsynapse
    of the hippocampal mossy fiber synapse.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Xiaoqi
      foaf_name: Geng, Xiaoqi
      foaf_surname: Geng
      foaf_workInfoHomepage: http://www.librecat.org/personId=3395256A-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Tomohiko
      foaf_name: Maruo, Tomohiko
      foaf_surname: Maruo
  - foaf_Person:
      foaf_givenName: Kenji
      foaf_name: Mandai, Kenji
      foaf_surname: Mandai
  - foaf_Person:
      foaf_givenName: Irwan
      foaf_name: Supriyanto, Irwan
      foaf_surname: Supriyanto
  - foaf_Person:
      foaf_givenName: Muneaki
      foaf_name: Miyata, Muneaki
      foaf_surname: Miyata
  - foaf_Person:
      foaf_givenName: Shotaro
      foaf_name: Sakakibara, Shotaro
      foaf_surname: Sakakibara
  - foaf_Person:
      foaf_givenName: Akira
      foaf_name: Mizoguchi, Akira
      foaf_surname: Mizoguchi
  - foaf_Person:
      foaf_givenName: Yoshimi
      foaf_name: Takai, Yoshimi
      foaf_surname: Takai
  - foaf_Person:
      foaf_givenName: Masahiro
      foaf_name: Mori, Masahiro
      foaf_surname: Mori
  bibo_doi: 10.1111/gtc.12508
  bibo_issue: '8'
  bibo_volume: 22
  dct_date: 2017^xs_gYear
  dct_identifier:
  - UT:000409224300003
  dct_isPartOf:
  - http://id.crossref.org/issn/1356-9597
  dct_language: eng
  dct_publisher: Wiley-Blackwell@
  dct_title: Roles of afadin in functional differentiations of hippocampal mossy fiber
    synapse@
...