---
res:
  bibo_abstract:
  - In the living cell, we encounter a large variety of motile processes such as organelle
    transport and cytoskeleton remodeling. These processes are driven by motor proteins
    that generate force by transducing chemical free energy into mechanical work.
    In many cases, the molecular motors work in teams to collectively generate larger
    forces. Recent optical trapping experiments on small teams of cytoskeletal motors
    indicated that the collectively generated force increases with the size of the
    motor team but that this increase depends on the motor type and on whether the
    motors are studied in vitro or in vivo. Here, we use the theory of stochastic
    processes to describe the motion of N motors in a stationary optical trap and
    to compute the N-dependence of the collectively generated forces. We consider
    six distinct motor types, two kinesins, two dyneins, and two myosins. We show
    that the force increases always linearly with N but with a prefactor that depends
    on the performance of the single motor. Surprisingly, this prefactor increases
    for weaker motors with a lower stall force. This counter-intuitive behavior reflects
    the increased probability with which stronger motors detach from the filament
    during strain generation. Our theoretical results are in quantitative agreement
    with experimental data on small teams of kinesin-1 motors.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Mehmet C
      foaf_name: Ucar, Mehmet C
      foaf_surname: Ucar
      foaf_workInfoHomepage: http://www.librecat.org/personId=50B2A802-6007-11E9-A42B-EB23E6697425
    orcid: 0000-0003-0506-4217
  - foaf_Person:
      foaf_givenName: Reinhard
      foaf_name: Lipowsky, Reinhard
      foaf_surname: Lipowsky
  bibo_doi: 10.1021/acs.nanolett.9b04445
  bibo_issue: '1'
  bibo_volume: 20
  dct_date: 2020^xs_gYear
  dct_identifier:
  - UT:000507151600087
  dct_isPartOf:
  - http://id.crossref.org/issn/1530-6984
  - http://id.crossref.org/issn/1530-6992
  dct_language: eng
  dct_publisher: American Chemical Society@
  dct_title: Collective force generation by molecular motors is determined by strain-induced
    unbinding@
  fabio_hasPubmedId: '31797672'
...